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Table 1 Comparison of demographics and clinical characteristics between ejection fractions

From: Evaluation of the prescribing practice of guideline-directed medical therapy among ambulatory chronic heart failure patients

Comorbidities (%)

Total (n = 1056)

Reduced (LVEF < 40) (n = 594)

Mid-range (LVEF = 41–49) (n = 136)

Preserved (LVEF > 50) (n = 326)

P-value

Age (years), median (IQR)

78 (68–84)

74 (63–82)

80 (70–84)

81 (75–85.2)

 < 0.001***

Weight (Kg), median (IQR)

77 (65–91.2)

76 (65–91)

76.5 (63–93)

80 (66–94)

0.410

SBP (mmHg), median (IQR)

120 (106–135)

114 (101–130)

122 (110–135)

130 (115–144)

 < 0.001***

DBP (mmHg), median (IQR)

65 (60–75)

65 (60–76)

65.5 (60–77)

67 (60–75)

0.583

HR (beats/min), median (IQR)

70 (60–80)

71 (61–81)

68 (60–80)

70 (60–81)

0.101

Number of medications used in first appointment, median (IQR)

10 (8–13)

10 (7–13)

10 (8–13)

11 (9–14)

 < 0.001***

Serum creatinine (mg/dl), median (IQR)

110 (82–152)

112 (86–154.2)

120.5 (86.2–152)

101 (77.2–142.5)

0.058

Hemoglobin (g/L), median (IQR)

120 (108–134)

124 (111–138)

120 (108–129)

119 (105–131)

0.001**

MCV (fL/red cells), median (IQR)

89.5 (86–93.5)

89.2 (86.2–94)

90.2 (85–94)

89.5 (85–93)

0.736

Comorbidities (%)

Total (n = 1056)

Reduced (LVEF < 40) (n = 594)

Mid-range (LVEF = 41–49) (n = 136)

Preserved (LVEF > 50) (n = 326)

P-value

Hypertension

690 (65.3)

329 (55.4)

94 (69.1)

267 (82.0)

 < 0.001***

IHD

592 (56.1)

338 (57.0)

87 (64.0)

167 (51.2)

0.035*

AF

497 (47.1)

261 (44.0)

64 (47.1)

172 (53.0)

0.037*

Hyperlipidemia

529 (50.1)

285 (48.0)

79 (58.1)

165 (51.0)

0.102

Diabetes

450 (43.0)

239 (40.2)

58 (43.0)

153 (47.0)

0.145

Osteoarthritis

211 (20.0)

88 (15.0)

29 (21.3)

94 (29.0)

 < 0.001***

CRF

328 (3.1)

185 (31.1)

42 (31.0)

101 (31.0)

0.998

COPD

242 (23.0)

127 (21.4)

33 (24.3)

82 (25.2)

0.395

Anemia

204 (19.3)

84 (14.1)

29 (21.3)

91 (28)

 < 0.001***

Depression/Anxiety

176 (17.0)

95 (16.0)

19 (14.0)

62 (19)

0.332

Any cardiovascular accident

180 (17.0)

96 (16.2)

25 (18.4)

59 (18.1)

0.685

Asthma

94 (9.0)

41 (7.0)

13 (10.0)

40 (12.3)

0.023*

Any solid caner

155 (15.0)

83 (14.0)

22 (16.2)

50 (15.3)

0.744

  1. Test of significance between reduced, mid-range and preserved ejection fractions groups was performed by Kruskal–Wallis test for all the variables. p < .05 was considered significant. LVEF, left ventricular ejection fraction; SBP, systolic blood pressure; DBP, diastolic blood pressure; HR, heart rate; MCV, mean cell volume; IQR, interquartile range; IHD, ischemic heart disease; AF, atrial fibrillation; CRF, chronic renal failure; COPD, chronic obstructive pulmonary disease. *p < .05; **p < .01; ***p < .001