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Table 2 Three functional description terms with best-scoring p-value of each MCODE identified network

From: Bioinformatics analysis of common key genes and pathways of intracranial, abdominal, and thoracic aneurysms

Network Annotations #1 Annotations #2 Annotations #3
MCODE ALL GO:0007204 positive regulation of cytosolic calcium ion concentration GO:0046649 lymphocyte activation GO:0051480 regulation of cytosolic calcium ion concentration
MCODE 1 R-HSA-373076 Class A/1 (Rhodopsin-like receptors) R-HSA-418594 G alpha (i) signalling events R-HSA-500792 GPCR ligand binding
MCODE 2 hsa04660 T cell receptor signaling pathway M88 PID CD8 TCR PATHWAY M272 PID CD8 TCR DOWNSTREAM PATHWAY
MCODE 4 R-HSA-445355 Smooth Muscle Contraction R-HSA-397014 Muscle contraction GO:0006936 muscle contraction
MCODE 5 R-HSA-983695 Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983705 Signaling by the B Cell Receptor (BCR) GO:0050853 B cell receptor signaling pathway
MCODE 6 hsa04064 NF-kappa B signaling pathway R-HSA-5668541 TNFR2 non-canonical NF-kB pathway R-HSA-5676594 TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway
MCODE 7 R-HSA-5663213 RHO GTPases Activate WASPs and WAVEs R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation R-HSA-9664407 Parasite infection
MCODE 8 hsa05200 Pathways in cancer     
MCODE 10 R-HSA-416476 G alpha (q) signalling events R-HSA-373076 Class A/1 (Rhodopsin-like receptors) R-HSA-500792 GPCR ligand binding