Fig. 1

Pictorial presentation of the self-controlled case-series method applied in our study. Two possible scenarios for the timing of cardiovascular events (AMI or Stroke or Pulmonary embolism) and vaccination are shown. a Participant is followed from the start of the study period, has a CVD event at risk-period following vaccination. b Participant is followed from the start of the study period, has a CVD event at baseline following vaccination