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Table 2 Summary results of lipid profile values and prognosis in patients with coronary heart disease

From: Lipid profile and prognosis in patients with coronary heart disease: a meta-analysis of prospective cohort studies

Factors Outcomes References RR and 95% CI P value Heterogeneity (%) P value for heterogeneity
TC per SD increase MACE [36,37,38,39] 0.88 (0.67–1.17) 0.380 67.4 0.015
All-cause mortality [20, 37] 0.88 (0.74–1.04) 0.131 50.6 0.155
Cardiac death [19,20,21] 1.06 (0.98–1.16) 0.150 79.7 0.007
TC (low versus high) MACE [21, 29] 0.84 (0.56–1.26) 0.389 56.6 0.129
Cardiac death [21, 28] 0.82 (0.47–1.43) 0.486 79.2 0.028
TG per SD increase MACE [36, 38, 39] 0.99 (0.99–1.00) 0.004 41.4 0.163
TG (high versus low) MACE [21, 30, 35] 1.13 (0.96–1.33) 0.134 22.5 0.275
LDL-C per SD increase MACE [23, 36, 38, 39] 1.00 (0.99–1.02) 0.640 81.4 < 0.001
LDL-C (high versus low) MACE [21, 25, 35] 1.12 (0.80–1.55) 0.512 69.7 0.037
All-cause mortality [25, 31] 1.01 (0.21–4.77) 0.994 84.1 0.012
Cardiac death [28, 31] 2.25 (0.87–5.79) 0.093 59.6 0.116
HDL-C per SD increase MACE [23, 36, 38, 39] 0.86 (0.67–1.11) 0.252 76.5 0.002
All-cause mortality [20, 21, 29] 0.97 (0.93–1.00) 0.065 85.2 < 0.001
Cardiac death [20, 21, 29] 0.94 (0.89–1.00) 0.048 89.2 < 0.001
HDL-C (low versus high) MACE [21, 24, 27, 32, 34, 35] 1.24 (1.09–1.42) 0.002 0.0 0.462
All-cause mortality [26, 27, 29, 31] 1.52 (1.09–2.12) 0.014 64.0 0.025
Cardiac death [27,28,29, 31] 1.44 (1.11–1.87) 0.006 29.8 0.223
Lipoprotein(a) (high vs low) MACE [23, 33, 39] 1.47 (1.16–1.87) 0.001 0.0 0.386