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Table 3 Cox regression analyses of factors associated with the occurrence of MACCE after angioplasty in a 10-year follow-up

From: Risk factors associated with major adverse cardiac and cerebrovascular events following percutaneous coronary intervention: a 10-year follow-up comparing random survival forest and Cox proportional-hazards model

Variable Unadjusted hazard ratio 95% CI P value Adjusted hazard ratio 95% CI P value
Diabetes    < 0.001    0.003
 No Reference    Reference   
 Yes 3.01 1.95–4.64   2.17 1.29–3.66  
Smoking    0.001    < 0.001
 No Reference    Reference   
 Yes 2.04 1.36–3.07   2.41 1.46–3.98  
Age (years) 1.03 1.02–1.05 < 0.001 1.03 1.01–1.05 < 0.001
Stent length    0.007    0.016
 ≤ 20 mm Reference    Reference   
 > 20 mm 1.73 1.15–2.58   1.74 1.107–2.75  
Setting    0.192    0.186
 ACS Reference    Reference   
 CSA 1.205 0.91–1.59   0.73 0.46–1.16  
Hyperlipidemia    0.093    0.692
 No Reference    Reference   
 Yes 1.44 0.94–2.21   1.106 0.66–1.83  
Number of stents    0.11    
 1 Reference    Reference   
 2 0.62 0.34–1.12 0.658 0.79 0.46–1.34 0.382
 3 0.52 0.27–0.97 0.028 1.8 0.82–3.94 0.138
Sex    0.904    0.865
 Female Reference    Reference   
 Male 0.97 0.63–1.05   1.05 0.59–1.85  
PCI    0.55    0.799
 Ad hoc Reference    Reference   
 Elective 1.13 0.75–1.69   0.94 0.61–1.45  
Type of stent    0.75    0.166
 BMS Reference    Reference   
 DES 0.93 0.61–1.41   1.41 0.86–2.301  
Stent diameter    0.992    0.534
 3 mm Reference    Reference   
 3.5 mm 0.98 0.63–1.49 0.175 0.75 0.47–1.203 0.239
 4 mm 0.97 0.47–1.97 0.187 1 0.46–2.14 0.999
Number of vessels    0.208    0.344
 1 Reference    Reference   
 2 1.19 0.75–1.87 0.451 1.39 0.84–2.31 0.198
 3 1.64 0.94–2.87 0.078 1.45 0.77–2.74 0.245
Hypertension    0.031    0.526
 No Reference    Reference   
 Yes 1.55 1.04–2.32   1.16 0.72–1.9  
  1. *The covariates are ordered by decreasing VIMP in the RSF model