Characteristic | Univariate logistic regression | Multivariate logistic regression (model 1) | Multivariate logistic regression (model 2) | |||
---|---|---|---|---|---|---|
OR (95%CI) | P value | OR (95%CI) | P value | OR (95%CI) | P value | |
Age | 1.55 (1.011–1.101) | 0.014 |  |  |  |  |
Preoperative | Â | Â | Â | Â | Â | Â |
 APACHE II score | 1.194 (1.051–1.356) | 0.006 |  |  |  |  |
 CKD (eGFR < 60 ml/min) | 1.233 (0.582–2.614) | 0.584 |  |  |  |  |
 EuroSCORE II | 1.435 (1.103–1.867) | 0.007 |  |  |  |  |
Intraoperative | Â | Â | Â | Â | Â | Â |
 Operative time | 1.570 (1.208 – 2.041) | 0.001 |  |  |  |  |
 CPB time | 1.007 (1.001–1.013) | 0.018 |  |  |  |  |
 Amount of blood transfusion | 1.078 (1.021 – 1.139) | 0.007 |  |  | 1.078 (1.000–1.162) | 0.049 |
Postoperative | Â | Â | Â | Â | Â | Â |
 MAP | 0.962 (0.927–0.998) | 0.038 |  |  |  |  |
 The total amount of blood transfusion | 1.077 (1.050–1.103) |  < 0.001 |  |  |  |  |
 Mechanical ventilation time | 2.734 (1.903–3.928) |  < 0.001 |  |  |  |  |
 SOFA score | 1.538 (1.283–1.845) |  < 0.001 |  |  |  |  |
 Hb | 0.976 (0.957–0.995) | 0.015 |  |  |  |  |
 PLT | 0.985 (0.977–0.993) |  < 0.001 |  |  |  |  |
 AKI | 7.539 (1.709–33.251) | 0.008 |  |  |  |  |
 Advanced AKI | 29.732 (11.507–76.821) |  < 0.001 | 19.408 (6.553–57.482) |  < 0.001 | 16.560 (5.154–53.212) |  < 0.001 |
Use of CRRT | 18.939 (6.485 – 55.313) | 0.001 |  |  |  |  |
Use of PE/BA | 15.846 (1.848 – 135.879) | 0.012 |  |  |  |  |
Use of ECMO | 22.270 (2.693–184.155) | 0.004 |  |  |  |  |
Peak TB concentration | 1.018 (1.001–1.025) |  < 0.001 |  |  |  |  |
Peak direct bilirubin concentration | 1.024 (1.015–1.033) |  < 0.001 |  |  |  |  |
Peak indirect bilirubin concentration | 1.013 (1.001–1.026) | 0.035 |  |  |  |  |
Time to peak TB concentration | 1.808 (1.458–2.242) |  < 0.001 | 1.557 (1.259–1.926) |  < 0.001 |  |  |
Time to peak TB concentration ≥ 5 days | 25.850 (10.218–65.399) |  < 0.001 |  |  | 22.384 (6.767–74.035) |  < 0.001 |
ICU stay time | 1.285 (1.152–1.433) |  < 0.001 |  |  |  |  |