Skip to main content

Table 3 Logistic regression analysis for in-hospital mortality

From: Time to peak bilirubin concentration and advanced AKI were associated with increased mortality in rheumatic heart valve replacement surgery patients with severe postoperative hyperbilirubinemia: a retrospective cohort study

Characteristic

Univariate logistic regression

Multivariate logistic regression (model 1)

Multivariate logistic regression (model 2)

OR (95%CI)

P value

OR (95%CI)

P value

OR (95%CI)

P value

Age

1.55 (1.011–1.101)

0.014

    

Preoperative

      

 APACHE II score

1.194 (1.051–1.356)

0.006

    

 CKD (eGFR < 60 ml/min)

1.233 (0.582–2.614)

0.584

    

 EuroSCORE II

1.435 (1.103–1.867)

0.007

    

Intraoperative

      

 Operative time

1.570 (1.208 – 2.041)

0.001

    

 CPB time

1.007 (1.001–1.013)

0.018

    

 Amount of blood transfusion

1.078 (1.021 – 1.139)

0.007

  

1.078 (1.000–1.162)

0.049

Postoperative

      

 MAP

0.962 (0.927–0.998)

0.038

    

 The total amount of blood transfusion

1.077 (1.050–1.103)

 < 0.001

    

 Mechanical ventilation time

2.734 (1.903–3.928)

 < 0.001

    

 SOFA score

1.538 (1.283–1.845)

 < 0.001

    

 Hb

0.976 (0.957–0.995)

0.015

    

 PLT

0.985 (0.977–0.993)

 < 0.001

    

 AKI

7.539 (1.709–33.251)

0.008

    

 Advanced AKI

29.732 (11.507–76.821)

 < 0.001

19.408 (6.553–57.482)

 < 0.001

16.560 (5.154–53.212)

 < 0.001

Use of CRRT

18.939 (6.485 – 55.313)

0.001

    

Use of PE/BA

15.846 (1.848 – 135.879)

0.012

    

Use of ECMO

22.270 (2.693–184.155)

0.004

    

Peak TB concentration

1.018 (1.001–1.025)

 < 0.001

    

Peak direct bilirubin concentration

1.024 (1.015–1.033)

 < 0.001

    

Peak indirect bilirubin concentration

1.013 (1.001–1.026)

0.035

    

Time to peak TB concentration

1.808 (1.458–2.242)

 < 0.001

1.557 (1.259–1.926)

 < 0.001

  

Time to peak TB concentration ≥ 5 days

25.850 (10.218–65.399)

 < 0.001

  

22.384 (6.767–74.035)

 < 0.001

ICU stay time

1.285 (1.152–1.433)

 < 0.001

    
  1. ACC, aortic cross clamp; AKI, acute kidney injury; APACHEII, acute physiology and chronic health evaluation II; BA, bilirubin adsorption; CPB, cardiopulmonary bypass; CRRT, continuous renal replacement therapy; ECMO, extracorporeal membrane oxygenation; eGFR, estimated glomerular filtration rate; Hb, hemoglobin; ICU, intensive care unit; MAP, mean arterial pressure; PE, plasma exchange; PLT, platelet; SOFA, sequential organ failure assessment; TB, total bilirubin