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Table 1 Baseline characteristics in patients developing hyperbilirubinemia

From: Time to peak bilirubin concentration and advanced AKI were associated with increased mortality in rheumatic heart valve replacement surgery patients with severe postoperative hyperbilirubinemia: a retrospective cohort study

Variables Value
Preoperative  
Age (years) 52.11 ± 9.28
Male, n (%) 53 (35.6%)
Hypertension, n (%) 11 (7.4%)
Diabetes, n (%) 2 (1.3%)
Atrial fibrillation, n (%) 53 (35.6%)
eGFR (ml/min) 67.05 ± 15.06
CKD (eGFR < 60 ml/min) 45 (30.2%)
 Stage 3 (30 ml/min ≤ eGFR < 60 ml/min) 43 (28.9%)
 Stage 4 (15 ml/min ≤ eGFR < 30 ml/min) 1 (0.7%)
 Stage 5 (eGFR < 15 ml/min 1 (0.7%)
EuroSCORE II 1.8 ± 1.3
APACHE II score 6.29 ± 2.78
MELD score 9.88 ± 4.47
SOFA score 1.87 ± 1.54
MAP (mmHg) 86.95 ± 12.14
TB (µmol/l) 28.86 ± 15.93
WBC (109/l) 6.20 ± 2.21
Hb (g/l) 136.30 ± 19.33
PLT (109 /l) 168.87 ± 58.26
Cr (µmol/l) 98.80 ± 38.05
Cys-C (mg/l) 1.169 ± 0.537
PT (s) 13.49 ± 4.36
Intra-operative  
 Type of surgery  
  Single aortic valve, n (%) 9 (6.0%)
  Single mitral valve, n (%) 25 (16.8%)
  Single tricuspid valve, n (%) 3 (2.0%)
  Aortic valve + mitral valve, n (%) 19 (12.8%)
  Aortic valve + tricuspid valve, n (%) 1 (0.7%)
  Mitral valve + tricuspid valve, n (%) 28 (18.8%)
  Aortic valve + mitral valve + tricuspid valve, n (%) 63 (42.3%)
  Valve + CABG, n (%) 3 (2.0%)
Operation duration (h) 4.32 ± 1.48
CPB time (min) 161.16 ± 60.46
ACC time (min) 89.40 ± 35.04
Blood transfusion requirement (U) 4.86 ± 7.08
Number of valve replacements 2.14 ± 0.83
Postoperative  
APACHE II score 17.77 ± 1.92
SOFA score 11.38 ± 2.44
MELD score 16.48 ± 4.49
TB (µmol /l) 69.80 ± 28.11
CB (µmol /l) 29.72 ± 13.02
WBC (109/l) 14.48 ± 5.35
Hb (g/l) 119.41 ± 19.07
PLT (109/l) 124.39 ± 52.73
Cr (µmol/l) 137.07 ± 35.24
PT (s) 13.60 ± 2.43
Peak TB level (µmol/l) 155.34 ± 82.11
Peak direct bilirubin level (µmol/l) 98.10 ± 65.90
Peak indirect bilirubin level (µmol/l) 57.24 ± 29.00
Time to peak TB (d) 4.18 ± 3.42
  1. ACC, aortic cross clamp; APACHEII, acute physiology and chronic health evaluation II; CABG, coronary artery bypass grafting; CPB, cardiopulmonary bypass; Cys-c, cystatin C; eGFR, estimated glomerular filtration rate; Hb, hemoglobin; MAP, mean arterial pressure; MELD, model for end-stage liver disease; min, minute; PLT, platelet; PT, prothrombin time; SCr, serum creatinine; SOFA, sequential organ failure assessment; TB, total bilirubin; WBC, white blood cell