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Table 2 Echographic and biological characteristics of Black hypertensive patients, stratified by the presence or absence of LVH

From: Association between insulin resistance and left ventricular hypertrophy in asymptomatic, Black, sub-Saharan African, hypertensive patients: a case–control study

Variables

LVH + 

n = 88

LVH − 

n = 132

P

Echocardiographic measurements

   

LVED (mm)

46.5 ± 4.4

42.9 ± 4.1

 < 0.001

IVS (mm)

12.7 ± 1.1

10.7 ± 1.5

 < 0.001

PWT (mm)

12.5 ± 0.8

10.7 ± 1.5

 < 0.001

SWT (mm)

25.2 ± 1.6

21.3 ± 2.9

 < 0.001

LVEF (%)

63.8 ± 5.4

65.1 ± 4.9

0.062

LVM (g)

222.2 ± 38.4

156.8 ± 34.8

 < 0.001

LVMIh (g/m2,7)

54.7 ± 8.4

37.6 ± 6.6

 < 0.001

LVMIbsa (g/m2)

108.5 ± 15.7

79.7 ± 15.0

 < 0.001

RWT

0.55 ± 0.1

0.50 ± 0.1

0.001

E (Cm/s)

0.85 ± 0.6

1.08 ± 0.6

0.029

E/A ratio

0.71 ± 0.2

0.99 ± 0.2

0.034

DT (ms)

215.8 ± 39.4

172.8 ± 37.7

 < 0.001

E/e’ ratio

7.4 (4.9–7.5)

5.5 (4.5–7.0)

˂ 0.001

LAA (cm2)

17.3 ± 3.5

14.7 ± 2.7

˂ 0.001

SPAP (mmHg)

26.9 ± 3.1

26.0 ± 2.7

0.019

Biological parameters

   

TC (mmol/L)

5.5 ± 1.0

5.4 ± 1.0

0.305

LDL-c (mmol/L)

3.8 ± 1.1

3.6 ± 1.1

0.126

Triglycerides (mmol/L)

1.25 ± 0.6

1.05 ± 0.6

0.027

HDL-c (mmol/L)

1.1 ± 0.3

1.3 ± 0.4

0.003

Glycemia (mmol/L)

6.3 ± 2.1

5.4 ± 1.6

 < 0.001

HbA1C (%)

6.3 ± 1.6

5.9 ± 1.1

0.016

Insulinemia (mmol/L)

122.8 ± 43.1

72.7 ± 25.8

 < 0.001

AI

5.2 ± 1.6

4.6 ± 1.8

0.008

HOMA-IR

2.36 ± 0.8

1.41 ± 0.6

0.014

Uric acid (mmol/L)

388.3 ± 98.4

352.9 ± 89.5

0.007

Creatinine (mmol/L)

84.7 ± 22.6

84.3 ± 16.2

0.854

Calcium (mmol/L)

2.30 ± 0.2

2.3 ± 0.2

0.105

Ionized calcium (mmol/L)

1.20 ± 0.11

1.22 ± 0.2

0.331

Phosphorus (mmol/L)

1.06 ± 0.2

1.09 ± 0.3

0.333

Dyslipidemia

75 (85.2)

98 (74.2)

0.036

High AI

45 (51.1)

48 (36.4)

0.021

T2DM

20 (22.7)

23 (17.4)

0.212

Hyperinsulinemia

8 (9.1)

11 (8.3)

0.514

IR

42 (47.7)

2 (1.5)

 < 0.001

Hyperuricemia

29 (33.0)

22 (16.7)

0.004

  1. LVED = left ventricular end-diastolic diameter; IVS = interventricular septal thickness; PWT = posterior wall thickness; SWT = sum of wall thickness; LVEF = left ventricular ejection fraction; LVM = left ventricular mass; LVMIh = left ventricular mass indexed to height2,7; LVMbsa = left ventricular mass indexed to body surface area; RWT = relative wall thickness; E = mitral E wave; E/A = ratio of peak early and late diastolic flow velocities; DT = deceleration time; e’ = mitral annular early diastolic velocity; LAA = left atrium area; SPAP = systolic pulmonary arterial pressure; TC = total cholesterol; LDL-c = low-density lipoprotein cholesterol; HDL-c = high-density lipoprotein; AI = atherogenicity index; HbA1C = glycated hemoglobin; T2DM = type 2 diabetes mellitus; HOMA-IR = homeostatic model assessment for insulin resistance; IR = insulin resistance