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Table 3 Age and cardiovascular risk factors in relation to quartiles of log ALT in women (mean and SD or numbers and %)

From: Serum alanine aminotransferase activity and risk factors for cardiovascular disease in a Caucasian population: the Tromsø study

Variables

Log ALT quartiles

P (trend)

Log ALT (U/L)

 < 1.23

1.23 – 1.34

1.35–1.46

 > 1.46

 

N

717

745

684

712

 

Age (years)

56.3 (15.0)

60.8 (12.7)

61.9 (11.6)

60.9 (10.8)

 < 0.001

BMI (kg/m2)

25.2 (3.8)

26.1 (4.3)

27.0 (4.6)

28.4 (4.9)

 < 0.001

Waist-to-hip-ratio

0.86 (0.07)

0.86 (0.07)

0.87 (0.06)

0.89 (0.07)

 < 0.001

Systolic blood pressure (mmHg)

132.1 (26.0)

138.3 (25.8)

139.7 (25.0)

144.9 (25.9)

 < 0.001

Diastolic blood pressure (mmHg)

74.3 (10.6)

75.5 (10.2)

76.1 (10.0)

78.8 (11.1)

 < 0.001

Total/HDL cholesterol ratio

3.51 (1.06)

3.59 (1.00)

3.70 (1.16)

4.17 (1.28)

 < 0.001

Triglycerides (mmol/L)

1.27 (0.65)

1.31 (0.66)

1.43 (0.78)

1.70 (1.00)

 < 0.001

Log hs-CRP (mg/dl)

0.13 (0.49)

0.10 (0.44)

0.14 (0.43)

0.24 (0.41)

 < 0.001

Log s-glucose (mmol/L)

0.69 (0.07)

0.70 (0.06)

0.71 (0.06)

0.72 (0.08)

 < 0.001

Log HbA1C (%)

0.74 (0.04)

0.75 (0.04)

0.75 (0.04)

0.76 (0.05)

 < 0.001

Heavy exerciser†

94 (13.1)

126 (16.9)

113 (16.5)

43 (6.0)

0.85

Alcohol ≥ 2–3 times per week

122 (17.0)

139 (18.7)

120 (17.5)

127 (17.8)

0.88

  1. ALT alanine aminotransferase, BMI body mass index, HbA1C glycated haemoglobin, HDL high density lipoprotein, Hs-CRP high-sensitive C-reactive protein, SD standard deviation
  2. Moderate or hard leisure exercise ≥ 2 h per week