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Table 3 Age and cardiovascular risk factors in relation to quartiles of log ALT in women (mean and SD or numbers and %)

From: Serum alanine aminotransferase activity and risk factors for cardiovascular disease in a Caucasian population: the Tromsø study

Variables Log ALT quartiles P (trend)
Log ALT (U/L)  < 1.23 1.23 – 1.34 1.35–1.46  > 1.46  
N 717 745 684 712  
Age (years) 56.3 (15.0) 60.8 (12.7) 61.9 (11.6) 60.9 (10.8)  < 0.001
BMI (kg/m2) 25.2 (3.8) 26.1 (4.3) 27.0 (4.6) 28.4 (4.9)  < 0.001
Waist-to-hip-ratio 0.86 (0.07) 0.86 (0.07) 0.87 (0.06) 0.89 (0.07)  < 0.001
Systolic blood pressure (mmHg) 132.1 (26.0) 138.3 (25.8) 139.7 (25.0) 144.9 (25.9)  < 0.001
Diastolic blood pressure (mmHg) 74.3 (10.6) 75.5 (10.2) 76.1 (10.0) 78.8 (11.1)  < 0.001
Total/HDL cholesterol ratio 3.51 (1.06) 3.59 (1.00) 3.70 (1.16) 4.17 (1.28)  < 0.001
Triglycerides (mmol/L) 1.27 (0.65) 1.31 (0.66) 1.43 (0.78) 1.70 (1.00)  < 0.001
Log hs-CRP (mg/dl) 0.13 (0.49) 0.10 (0.44) 0.14 (0.43) 0.24 (0.41)  < 0.001
Log s-glucose (mmol/L) 0.69 (0.07) 0.70 (0.06) 0.71 (0.06) 0.72 (0.08)  < 0.001
Log HbA1C (%) 0.74 (0.04) 0.75 (0.04) 0.75 (0.04) 0.76 (0.05)  < 0.001
Heavy exerciser† 94 (13.1) 126 (16.9) 113 (16.5) 43 (6.0) 0.85
Alcohol ≥ 2–3 times per week 122 (17.0) 139 (18.7) 120 (17.5) 127 (17.8) 0.88
  1. ALT alanine aminotransferase, BMI body mass index, HbA1C glycated haemoglobin, HDL high density lipoprotein, Hs-CRP high-sensitive C-reactive protein, SD standard deviation
  2. Moderate or hard leisure exercise ≥ 2 h per week