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Table 2 Age and cardiovascular risk factors in relation to quartiles of log ALT in men (mean and SD or numbers and %)

From: Serum alanine aminotransferase activity and risk factors for cardiovascular disease in a Caucasian population: the Tromsø study

Variables Log ALT quartiles P (trend)
Log ALT (U/L)  < 1.32 1.32 – 1.44 1.45 – 1.58  ≥ 1.58
N 631 662 622 637  
Age (years) 64.1 (12.4) 61.1 (12.3) 59.6 (11.5) 56.5 (11.6)  < 0.001
BMI (kg/m2) 25.3 (3.3) 26.6 (3.2) 27.9 (3.5) 29.1 (5.0)  < 0.001
Waist-to-hip-ratio 0.93 (0.07) 0.95 (0.06) 0.95 (0.06) 0.98 (0.06)  < 0.001
Systolic blood pressure (mmHg) 140.0 (22.0) 140.1 (20.7) 141.7 (20.8) 140.8 (20.5) 0.50
Diastolic blood pressure (mmHg) 79.2 (10.0) 81.1 (10.1) 82.4 (10.0) 84.0 (10.6)  < 0.001
Total/HDL cholesterol ratio 3.88 (1.24) 4.15 (1.31) 4.35 (1.32) 4.73 (1.43)  < 0.001
Triglycerides (mmol/L) 1.39 (0.75) 1.55 (0.99) 1.72 (0.96) 1.97 (1.16)  < 0.001
Log hs-CRP (mg/dl) 0.16 (0.48) 0.13 (0.42) 0.15 (0.39) 0.22 (0.40) 0.10
Log s-glucose (mmol/L) 0.71 (0.07) 0.72 (0.07) 0.73 (0.07) 0.74 (0.09)  < 0.001
Log HbA1C (%) 0.76 (0.05) 0.76 (0.04) 0.76 (0.04) 0.77 (0.05) 0.007
Heavy exerciser† 98 (15.5) 131 (19.8) 104 (16.7) 98 (15.4) 0.64
Alcohol 2–3 times per week 134 (21.2) 159 (24.0) 146 (23.5) 156 (24.5) 0.24
  1. ALT alanine aminotransferase, BMI body mass index, HbA1C glycated haemoglobin, HDL high density lipoprotein, Hs-CRP high-sensitive C-reactive protein, SD standard deviation
  2. Moderate or hard leisure exercise ≥ 2 h per week