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Table 1 Basic characteristics and endpoints of the participants presented as mean (SD) or numbers (%)

From: Serum alanine aminotransferase activity and risk factors for cardiovascular disease in a Caucasian population: the Tromsø study

Variables Men (n = 2555) Women (n = 2858) P value
Age (year) 60.4 (12.2) 60.0 (12.8) 0.27
BMI (kg/m2) 27.3 (3.7) 26.7 (4.6)  < 0.001
Waist-to-hip-ratio 0.95 (0.06) 0.87 (0.07)  < 0.001
Obesity (BMI ≥ 30 kg/m2) 526 (20.6) 595 (20.8) 0.81
Heavy exerciser 431 (16.9) 433 (15.2) 0.056
Alcohol 2–3 times or more per week 595 (23.3) 511 (17.9)  < 0.001
Heavy alcohol drinker 72 (2.8) 15 (0.5)  < 0.001
Systolic blood pressure (mmHg) 140.6 (21.0) 138.2 (25.7)  < 0.001
Diastolic blood pressure (mmHg) 81.7 (10.3) 76.0 (10.3)  < 0.001
Hypertension 1275 (49.9) 1293 (45.2) 0.001
Diabetes 151 (5.9) 130 (4.5) 0.031
Coronary heart disease 252 (9.9) 86 (3.0)  < 0.001
Total cholesterol (mmol/L) 5.50 (1.08) 5.81 (1.11)  < 0.001
HDL cholesterol (mmol/L) 1.37 (0.38) 1.66 (0.44)  < 0.001
LDL cholesterol (mmol/L) 3.54 (0.95) 3.63 (0.98) 0.001
Total/HDL cholesterol ratio 4.29 (1.36) 3.71 (1.13)  < 0.001
Triglycerides (mmol/L) 1.66 (0.99) 1.43 (0.80)  < 0.001
S-ALT (U/L) 32.62 (19.4) 26.30 (25.61)  < 0.001§
High s-ALT (U/L) 113 (4.4) 188 (6.6) 0.001
S-AST (U/L) 27.85 (9.96) 25.25 (14.15)  < 0.001§
S-GGT (U/L) 37.17 (39.16) 27.39 (37.95)  < 0.001§
S-creatinine (µmol/L) 77.91 (16.01) 61.83 (12.83)  < 0.001
Hs-CRP (mg/dl) 2.66 (5.17) 2.76 (5.76) 0.59
S-glucose (mmol/L) 5.42 (1.31) 5.17 (1.11)  < 0.001§
HbA1C (%) 5.78 (0.73) 5.69 (0.63)  < 0.001§
  1. ALT alanine aminotransferase, AST aspartate aminotransferase, BMI body mass index, HbA1C glycated haemoglobin, GGT gamma glutamyl transferase, HDL high density lipoprotein, Hs-CRP high-sensitive C-reactive protein, LDL low density lipoprotein, SD standard deviation
  2. Moderate or hard leisure exercise ≥ 2 h per week
  3. Drinking ≥ 6 alcohol units ≥ 2 times per week
  4. §Analyzed log-transformed