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Table 1 Clinical characteristics of the patients in the training and validation sets used to construct the nomogram, according to the in-hospital mortality status

From: Establishment and validation of a risk model for prediction of in-hospital mortality in patients with acute ST-elevation myocardial infarction after primary PCI

Clinical characteristics

Training set (n = 1169)

Validation set (n = 316)

 

In-hospital mortality (n = 95)

Survival (n = 1074)

P

In-hospital mortality (n = 25)

Survival (n = 291)

P

Male

60 (63.2)

816 (76.0)

0.006*

18 (72.0)

207 (71.1)

0.927

Age (years)

66.3 ± 13.3

59.6 ± 11.4

 < 0.001*

66.0 ± 14.2

60.0 ± 12.1

0.298

BMI (kg/m2)

25.0 ± 3.9

25.5 ± 3.3

0.011*

25.5 ± 4.0

25.4 ± 3.4

0.077

Drinking history

22 (23.2)

297 (27.7)

0.346

8 (32.0)

68 (23.4)

0.332

Smoking history

35 (36.8)

518 (48.2)

0.033*

8 (32.0)

121 (41.6)

0.350

DM history

26 (27.4)

214 (19.9)

0.085

7 (28.0)

59 (20.3)

0.362

Hypertension history

51 (53.7)

516 (48.0)

0.292

10 (40.0)

139 (47.8)

0.455

Killip classification

  

 < 0.001*

  

 < 0.001*

 I

35 (36.8)

939 (87.4)

 

12 (48.0)

262 (90.0)

 

 II

14 (14.7)

110 (10.2)

 

5 (20.0)

21 (7.2)

 

 III

8 (8.4)

18 (1.7)

 

1 (4.0)

6 (2.1)

 

 IV

38 (40.0)

7 (0.7)

 

7 (28.0)

2 (0.7)

 

LMCAD

7 (7.4)

3 (0.3)

 < 0.001*

2 (8.0)

1 (0.3)

 < 0.001*

Grading of thrombus

  

0.005*

  

0.340

 0

0

6 (0.6)

 

0

2 (0.7)

 

 1

0

15 (1.4)

 

3 (12.0)

5 (1.7)

 

 2

2 (2.1)

96 (8.9)

 

3 (12.0)

32 (11.0)

 

 3

29 (30.5)

450 (41.9)

 

6 (24.0)

131 (45.0)

 

 4

44 (46.3)

348 (32.4)

 

10 (40.0)

94 (32.3)

 

 5

20 (21.1)

159 (14.8)

 

3 (12.0)

42 (14.4)

 

TIMI classification

  

 < 0.001*

  

 < 0.001*

 0

16 (16.8)

1 (0.1)

 

6 (24.0)

0

 

 1

10 (10.2)

2 (0.2)

 

3 (12.0)

1 (0.3)

 

 2

12 (12.6)

57 (5.3)

 

2 (8.0)

15 (5.1)

 

 3

57 (60.0)

1014 (94.4)

 

14 (56.0)

275 (94.5)

 

Slow flow

41 (43.2)

86 (8.0)

 < 0.001*

7 (28.0)

25 (8.6)

 < 0.001*

Application of IABP

18 (19.0)

14 (1.3)

 < 0.001*

4 (16.0)

3 (1.0)

 < 0.001*

Administration of β-blocker

32 (33.7)

809 (75.3)

 < 0.001*

6 (24.0)

236 (81.1)

 < 0.001*

ACEI/ARB

20 (21.1)

644 (60.0)

 < 0.001*

5 (20.0)

186 (63.9)

0.003*

Symptom-to-door time (min)

256 ± 235

89 ± 73

 < 0.001*

248 ± 226

85 ± 74

 < 0.001*

Symptom-to-balloon time (min)

426 ± 244

236 ± 153

 < 0.001*

420 ± 269

234 ± 157

 < 0.001*

Syntax score

29.3 ± 9.9

20.7 ± 7.7

0.003*

31.9 ± 13.1

20.9 ± 7.9

0.003*

EF (%)

47.2 ± 8.5

54.6 ± 8.1

0.918

45.1 ± 7.4

54.7 ± 7.64

0.926

CK-MB (U/L)

180.0 ± 157.2

156.4 ± 58.2

 < 0.001*

175.3 ± 197.5

158.9 ± 54.7

0.019*

Random blood glucose (mmol/L)

9.25 ± 3.51

8.06 ± 2.83

0.056

9.3 (7.4,15.71)

7.1 (6.19,9.28)

0.001*

Triglycerides (mmol/L)

1.42 (1.01,1.80)

1.43 (0.99,1.99)

0.687

1.28 (0.98,1.71)

1.49 (0.99,1.99)

0.290

  1. *P < 0.05 between the in-hospital mortality and survival groups
  2. BMI body mass index, DM diabetes mellitus, LMCAD left main coronary artery disease, TIMI thrombolysis in myocardial infarction, IABP intra-aortic balloon pump, ACEI angiotensin-converting enzyme inhibitor, ARB angiotensin receptor blocker, EF ejection fraction, CK-MB creatinine kinase MB