Unadjusted | Adjusted (model 1)a,d | Adjusted (model 2)b,d | Adjusted (model 3)c,d | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
OR | 95% CI | P | OR | 95% CI | P | OR | 95% CI | P | OR | 95% CI | P | |
Lactate, baseline | 1.15 | 1.00–1.39 | 0.04 | 1.13 | 0.98–1.37 | 0.09 | 1.19 | 1.01–1.48 | 0.03 | 1.21 | 1.01–1.55 | 0.03 |
Lactate, 1 h | 1.13 | 1.00–1.33 | 0.05 | 1.11 | 0.97–1.32 | 0.14 | 1.21 | 1.02–1.50 | 0.02 | 1.29 | 1.07–1.73 | 0.005 |
Lactate, 6 h | 1.18 | 1.03–1.47 | 0.01 | 1.16 | 1.01–1.45 | 0.03 | 1.27 | 1.07–1.64 | 0.004 | 1.34 | 1.10–1.95 | 0.01 |
Lactate, 12 h | 1.27 | 1.05–1.76 | 0.005 | 1.25 | 1.04–1.74 | 0.01 | 1.46 | 1.13–2.22 | 0.001 | 1.62 | 1.19–3.03 | < 0.001 |
Lactate, 24 h | 1.76 | 1.13–4.33 | 0.001 | 1.63 | 1.11–3.88 | 0.001 | 2.37 | 1.24–6.90 | < 0.001 | 5.86 | 1.53–67.86 | < 0.001 |
Overall lactatee | 1.27 | 1.06–1.70 | 0.03 | 1.26 | 1.04–1.71 | 0.01 | 1.54 | 1.16–2.50 | < 0.001 | 1.73 | 1.20–3.48 | < 0.001 |
Clearance, 1hf,g | 1.00 | 0.98–1.01 | 0.60 | 1.00 | 0.98–1.01 | 0.81 | 0.99 | 0.97–1.01 | 0.31 | 0.99 | 0.97–1.01 | 0.10 |
Clearance, 6hf,g | 0.98 | 0.97–0.99 | 0.01 | 0.98 | 0.97–0.99 | 0.01 | 0.97 | 0.95–0.99 | 0.002 | 0.97 | 0.94–0.99 | 0.002 |
Clearance, 12hf,g | 0.98 | 0.96–0.99 | 0.006 | 0.98 | 0.96–0.99 | 0.005 | 0.97 | 0.94–0.99 | < 0.001 | 0.97 | 0.93–0.99 | < 0.001 |
Clearance, 24hf,g | 0.95 | 0.91–0.98 | < 0.001 | 0.95 | 0.90–0.99 | < 0.001 | 0.94 | 0.87–0.98 | < 0.001 | 0.97 | 0.78–0.98 | < 0.001 |