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Table 1 Demographic and laboratory data

From: Addition of routine blood biomarkers to TIMI risk score improves predictive performance of 1-year mortality in patients with ST-segment elevation myocardial infarction

 

All (n = 1057)

Mortality (−) (n = 982)

Mortality (+) (n = 75)

p value

Demographic data

 Age (years)

60.5 ± 13.1

59.7 ± 12.9

70.8 ± 11.0

< 0.001

 Men [n (%)]

837 (79.2)

784 (79.8)

53 (70.7)

0.075

 Body mass index (kg/m2)

24.1 ± 3.2

24.2 ± 3.2

23.0 ± 3.6

0.002

 Diabetes mellitus [n (%)]

279 (26.4)

250 (25.5)

29 (38.7)

0.020

 Hypertension [n (%)]

496 (46.9)

452 (46.0)

44 (58.7)

0.041

 Systolic blood pressure (mmHg)

125.1 ± 27.3

126.3 ± 26.7

109.0 ± 30.8

< 0.001

 Diastolic blood pressure (mmHg)

76.3 ± 17.5

77.0 ± 17.2

66.9 ± 19.2

< 0.001

 Heart rate (beats/minute)

77.5 ± 20.1

76.7 ± 19.5

87.3 ± 25.0

0.001

 Cardiogenic shock [n (%)]

66 (6.2)

47 (4.8)

19 (25.3)

< 0.001

 Killip class II–IV [n (%)]

209 (19.8)

168 (17.1)

41 (54.7)

< 0.001

 Anterior wall infarction [n (%)]

564 (69.3)

512 (52.1)

52 (69.3)

0.004

Laboratory data

 Albumin (g/dL)

4.2 ± 0.4

4.2 ± 0.4

3.8 ± 0.6

< 0.001

 Glucose (mg/dL)

177.7 ± 83.1

173.0 ± 74.6

239.4 ± 144.0

< 0.001

 Dysglycemia [n (%)]

159 (15.0)

126(12.8)

33 (44.0)

< 0.001

 Total bilirubin (mg/dL)

0.7 ± 0.4

0.7 ± 0.4

0.7 ± 0.5

0.245

 AST (IU/L)

33.0 (23.0–65.0)

32.0 (23.0–61.0)

72.0 (27.0–227.0)

< 0.001

 ALT (IU/L)

26.0 (19.0–42.0)

26.0 (19.0–41.0)

36.0 (18.0–78.0)

0.034

 Hypoxic liver injury† [n (%)]

236 (22.3)

199 (20.3)

37 (49.3)

< 0.001

 ALP (IU/L)

74.0 (61.0–91.1)

74.0 (61.0–90.0)

81.0 (65.0–98.0)

0.061

 Creatinine (mg/dL)

1.08 ± 0.73

1.06 ± 0.73

1.33 ± 0.67

0.001

 Estimated GFR (mL/min/1.73 m2)

82.1 ± 27.5

83.3 ± 26.8

65.8 ± 32.0

< 0.001

 Estimated GFR < 60 mL/min/1.73 m2 [n (%)]

184 (17.4)

152 (15.5)

32 (42.7)

< 0.001

 Hemoglobin (mg/dL)

14.2 ± 1.9

14.3 ± 1.9

13.1 ± 2.4

< 0.001

 Anemia [n (%)]

177 (16.7)

146 (14.9)

31 (41.3)

< 0.001

 WBC (× 103/µL)

12.0 ± 5.2

11.8 ± 5.2

13.9 ± 4.7

0.001

 NLR

3.1 (1.6–5.7)

3.0 (1.5–5.4)

5.4 (3.0–8.9)

< 0.001

 NLR > 4.3 [n (%)]

393 (37.2)

342 (34.8)

51 (68.0)

< 0.001

 Total cholesterol (mg/dL)

189.3 ± 43.7

190.6 ± 43.1

172.5 ± 47.8

0.001

 LDL-cholesterol (mg/dL)

117.0 ± 36.8

117.8 ± 36.7

106.6 ± 37.0

0.043

 HDL-cholesterol (mg/dL)

42.5 ± 11.0

42.6 ± 10.9

41.0 ± 11.7

0.305

 Triglyceride

129.0 (86.0–196.0)

131.0 (87.0–197.0)

111.0 (76.5–180.5)

0.100

 Initial CK-MB (ng/mL)

5.3 (2.1–26.5)

4.9 (2.1–22.5)

26.0 (3.6–96.1)

< 0.001

 Peak CK-MB (ng/mL)

177.4 (78.2–300.0)

170.9 (77.8–300.0)

271.0 (86.0–332.2)

0.016

  1. AST aspartate transaminase, ALT alanine transaminase, ALP alkaline phosphatase, GFR glomerular filtration rate, WBC white blood cell, NLR neutrophil to lymphocyte ratio, CK-MB creatine kinase-myocardial band isoenzyme
  2. *Dysglycemia was defined as serum glucose < 90 or > 250 mg/dL
  3. †Hypoxic liver injury was defined as an elevation of serum transaminases levels more than twice the upper limit of normal