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Table 5 Predictors of the occurrence of MACEs in patients with new-onset ACS: results of univariate and multivariate Cox-regression analysesss

From: Predictive efficacy of neutrophil-to-lymphocyte ratio for long-term prognosis in new onset acute coronary syndrome: a retrospective cohort study

Variables

Univariate

Multivariate

HR

95% CI

P

HR

95% CI

P

Sex (Male/Female)

1.275

0.694–2.342

0.433

   

Age

1.051

1.029–1.073

 < 0.001

1.049

1.024–1.075

 < 0.001

Hypertension

0.918

0.562–1.499

0.731

   

Diabetes mellitus

1.175

0.676–2.044

0.568

   

Smoking

 Former smoker vs never smoker

1.177

0.161–8.616

0.872

   

 Current smoker vs never smoker

0.842

0.516–1.374

0.490

   

Alcohol drinking

 Former smoker vs never drinking

1.061

0.526–2.139

0.868

   

 Current smoker vs never drinking

1.390

0.797–2.423

0.246

   

Family history of CAD

0.876

0.529–1.450

0.605

   

SBP (mmHg)

1.029

1.016–1.042

 < 0.001

1.029

1.009–1.049

0.005

DBP (mmHg)

1.040

1.019–1.059

 < 0.001

1.007

0.978–1.038

0.626

Heart rate

1.008

0.992–1.024

0.319

   

BMI

0.965

0.928–1.003

0.072

   

HDL-C (mmol/l)

2.371

0.909–6.183

0.078

   

LDL-C (mmol/l)

1.238

0.913–1.680

0.169

   

TC (mmol/l)

1.132

0.905–1.416

0.278

   

TG (mmol/l)

0.956

0.813–1.123

0.583

   

ApoA1 (g/L)

1.170

0.662–2.067

0.589

   

ApoB (g/L)

1.118

0.574–2.181

0.742

   

Lp(a) (g/L)

0.999

0.997–1.001

0.150

   

Creatinine (mmol/L)

1.001

0.994–1.006

0.995

   

BUN (mmol/l)

0.978

0.881–1.086

0.675

   

Uric acid (μmol/L)

1.001

0.997–1.003

0.980

   

NLR group

 2nd tertile vs 1st tertile

1.155

0.643–2.075

0.629

   

 3rd tertile vs 1st tertile

0.940

0.509–1.734

0.843

   

Monocyte count

0.923

0.427–1.996

0.839

   

PLR

1.001

0.999–1.002

0.080

   

RBC

1.534

1.015–2.318

0.042

1.452

0.991–1.038

0.056

HGB

1.002

0.993–1.012

0.660

   

PLT

1.001

0.999–1.002

0.550

   

MPV

1.001

0.847–1.180

0.997

   

PDW

0.946

0.882–1.016

0.126

   

PCT

1.654

0.177–15.465

0.659

   

WBC

0.979

0.913–1.049

0.540

   

Clinical diagnosis

 NSTEMI

1.062

0.386–2.9222

0.907

   

 STEMI

0.862

0.3692.012

0.731

   

UPLMT

2.446

1.301–4.599

0.006

1.466

0.763–2.816

0.251

LAD

2.155

0.783–5.929

0.137

   

LCX

1.430

0.836–2.445

0.191

   

RCA

2.186

1.080–4.423

0.030

1.242

0.598–2.579

0.561

Aspirin

1.085

0.495–2.377

0.838

   

Statins

1.230

0.562–2.695

0.605

   

β-Blockers

0.756

0.237–2.410

0.637

   

ACEI/ARB

0.813

0.199–3.323

0.773

   

CCB

0.866

0.413–1.815

0.703

   

PCI

0.614

0.280–1.345

0.223

   

Gensini group

 2nd tertile vs 1st tertile

2.631

1.159–5.973

0.021

1.989

0.861–4.596

0.107

 3rd tertile vs 1st tertile

5.076

2.363–10.900

 < 0.001

3.216

1.458–7.093

0.004