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Table 5 Predictors of the occurrence of MACEs in patients with new-onset ACS: results of univariate and multivariate Cox-regression analysesss

From: Predictive efficacy of neutrophil-to-lymphocyte ratio for long-term prognosis in new onset acute coronary syndrome: a retrospective cohort study

Variables Univariate Multivariate
HR 95% CI P HR 95% CI P
Sex (Male/Female) 1.275 0.694–2.342 0.433    
Age 1.051 1.029–1.073  < 0.001 1.049 1.024–1.075  < 0.001
Hypertension 0.918 0.562–1.499 0.731    
Diabetes mellitus 1.175 0.676–2.044 0.568    
Smoking
 Former smoker vs never smoker 1.177 0.161–8.616 0.872    
 Current smoker vs never smoker 0.842 0.516–1.374 0.490    
Alcohol drinking
 Former smoker vs never drinking 1.061 0.526–2.139 0.868    
 Current smoker vs never drinking 1.390 0.797–2.423 0.246    
Family history of CAD 0.876 0.529–1.450 0.605    
SBP (mmHg) 1.029 1.016–1.042  < 0.001 1.029 1.009–1.049 0.005
DBP (mmHg) 1.040 1.019–1.059  < 0.001 1.007 0.978–1.038 0.626
Heart rate 1.008 0.992–1.024 0.319    
BMI 0.965 0.928–1.003 0.072    
HDL-C (mmol/l) 2.371 0.909–6.183 0.078    
LDL-C (mmol/l) 1.238 0.913–1.680 0.169    
TC (mmol/l) 1.132 0.905–1.416 0.278    
TG (mmol/l) 0.956 0.813–1.123 0.583    
ApoA1 (g/L) 1.170 0.662–2.067 0.589    
ApoB (g/L) 1.118 0.574–2.181 0.742    
Lp(a) (g/L) 0.999 0.997–1.001 0.150    
Creatinine (mmol/L) 1.001 0.994–1.006 0.995    
BUN (mmol/l) 0.978 0.881–1.086 0.675    
Uric acid (μmol/L) 1.001 0.997–1.003 0.980    
NLR group
 2nd tertile vs 1st tertile 1.155 0.643–2.075 0.629    
 3rd tertile vs 1st tertile 0.940 0.509–1.734 0.843    
Monocyte count 0.923 0.427–1.996 0.839    
PLR 1.001 0.999–1.002 0.080    
RBC 1.534 1.015–2.318 0.042 1.452 0.991–1.038 0.056
HGB 1.002 0.993–1.012 0.660    
PLT 1.001 0.999–1.002 0.550    
MPV 1.001 0.847–1.180 0.997    
PDW 0.946 0.882–1.016 0.126    
PCT 1.654 0.177–15.465 0.659    
WBC 0.979 0.913–1.049 0.540    
Clinical diagnosis
 NSTEMI 1.062 0.386–2.9222 0.907    
 STEMI 0.862 0.3692.012 0.731    
UPLMT 2.446 1.301–4.599 0.006 1.466 0.763–2.816 0.251
LAD 2.155 0.783–5.929 0.137    
LCX 1.430 0.836–2.445 0.191    
RCA 2.186 1.080–4.423 0.030 1.242 0.598–2.579 0.561
Aspirin 1.085 0.495–2.377 0.838    
Statins 1.230 0.562–2.695 0.605    
β-Blockers 0.756 0.237–2.410 0.637    
ACEI/ARB 0.813 0.199–3.323 0.773    
CCB 0.866 0.413–1.815 0.703    
PCI 0.614 0.280–1.345 0.223    
Gensini group
 2nd tertile vs 1st tertile 2.631 1.159–5.973 0.021 1.989 0.861–4.596 0.107
 3rd tertile vs 1st tertile 5.076 2.363–10.900  < 0.001 3.216 1.458–7.093 0.004