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Table 4 Sex differences in cardiac damage in patients with severe type of COVID-19

From: Cardiac damage in patients with the severe type of coronavirus disease 2019 (COVID-19)

 

Median (IQR) or N (%)

p Value a

Men (n = 56)

Women (n = 44)

Age ≥ 60 y

31 (55.4)

29 (65.9)

0.285

Comorbidities

34 (60.7)

35 (79.5)

0.043

 Hypertension

18 (32.1)

22 (50.0)

0.070

 Diabetes

9 (16.1)

12 (27.3)

0.172

 CVD

5 (8.9)

10 (22.7)

0.055

 Hyperlipidemia

1 (1.8)

1 (2.3)

1.000

Cardiac damage

18 (32.1)

7 (15.9)

0.063

hsTnI, pg/ml

4.2 (1.9–12.8)

2.9 (1.9–7.4)

0.018

 Increased (> 34.2)

5 (10.4)

5 (11.6)

0.340

NTproBNP, pg/ml

272.5 (57.0–559.8)

86.0 (31.3–209.3)

0.013

 Increased#

18 (32.1)

4 (9.1)

0.006

  1. ap < .05 was considered statistically significant. COVID-19 = coronavirus disease 2019; CVD = cardiovascular disease; hsTnI = hypersensitive troponin I; NTproBNP = N-terminal-pro brain natriuretic peptide. #Increased NTproBNP was above 450 pg/ml at the age < 50, above 900 pg/ml at the age < 75, or above 1800 pg/ml at the age ≥ 75