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Table 1 Baseline characteristics of the study population

From: Blood group A: a risk factor for heart rupture after acute myocardial infarction

Variables

FWR patients (n = 40)

VSR patients (n = 15)

PMR patients (n = 6)

HR patients (n = 61)

Non-HR patients (n = 600)

P value (HR vs Non-HR)

Age, years

76.59 ± 5.48

74.36 ± 4.24

74.18 ± 5.02

75.56 ± 5.12

66.18 ± 6.63

< 0.001

Male, n (%)

16 (40)

7 (46.67)

3 (50)

26 (42.62)

427 (71.17)

< 0.001

HT, n (%)

27 (67.5)

9 (60)

3 (50)

39 (63.93)

420 (70)

0.571

DM, n (%)

9 (22.5)

4 (26.67)

2 (33.33)

15 (24.59)

145 (24.17)

0.433

CHF, n (%)

2 (5)

1 (6.67)

1 (16.67)

4 (6.56)

25 (4.17)

0.81

History of MI, n (%)

3 (7.5)

3 (20)

1 (16.67)

7 (11.48)

65 (10.83)

0.917

History of CAD, n (%)

6 (15)

4 (26.67)

2 (33.33)

12 (19.67)

115 (19.17)

0.743

History of PCI, n (%)

3 (7.5)

2 (13.33)

1 (16.67)

6 (9.84)

83 (13.83)

0.383

History of CABG, n (%)

1 (2.5)

1 (6.67)

0 (0)

2 (3.28)

13 (2.17)

0.419

Current smoker, n (%)

21 (52.5)

8 (53.33)

3 (50)

32 (52.46)

352 (58.67)

0.518

BMI, kg/m2

23.72 ± 3.14

23.44 ± 3.38

23.37 ± 3.04

23.51 ± 3.2

26.36 ± 3.43

< 0.001

Time from symptom onset to admission (h)

22 (8,68)

72 (12,160)

18 (4,50)

26 (9.8,94)

22 (8,98)

0.021

STEMI, n (%)

31 (77.5)

11 (73.33)

4 (66.67)

46 (75.41)

391 (65.17)

0.079

Anterior MI, n (%)

20 (50)

7 (46.67)

2 (33.33)

29 (47.54)

306 (51)

0.702

Heart rate, bpm

95.66 ± 16.72

104.21 ± 19.15

98.81 ± 20.04

99.33 ± 19.47

74.82 ± 16.2

 < 0.001

SBP, mmHg

114.47 ± 22.54

109.23 ± 21.24

109.7320.94

111.03 ± 24.1

127.17 ± 23.08

0.045

KILLIP class

      

 KILLIP I, n (%)

8 (20)

1 (6.67)

0 (0)

9 (16.36)

338 (56.33)

< 0.001

 KILLIP II, n (%)

20 (50)

9 (60)

2 (33.33)

31 (50.82)

201 (33.5)

< 0.001

 KILLIP III, n (%)

6 (15)

3 (20)

3 (50)

12 (19.67)

35 (5.83)

0.002

 KILLIP IV, n (%)

6 (15)

2 (13.3)

1 (16.67)

9 (14.75)

26 (4.33)

0.025

β-RB within 24 h, n (%)

12 (30)

6 (40)

2 (33.33)

20 (32.79)

303 (50.5)

0.071

ACEI/ARB within 24 h, n (%)

3 (7.5)

1 (6.67)

1 (16.67)

5 (8.2)

71 (11.83)

0.314

ESR, mm/h

24.28 ± 18.78

43.71 ± 29.7

37.4 ± 22.71

31.14 ± 23.48

12.15 ± 13.02

0.012

HBA1C, %

6.53 ± 1.01

6.39 ± 1.26

6.47 ± 1.11

6.44 ± 1.1

6.36 ± 0.98

0.102

BNP (pg/ml)

538.3 ± 304.63

1025.48 ± 406.22

849.06 ± 392.8

772.33 ± 368.09

274.78 ± 146.53

< 0.001

WBC, *109/L

12.23 ± 4.79

11.64 ± 4.23

12.01 ± 4.49

12.11 ± 4.62

9.66 ± 3.27

< 0.001

RBC, *1012/L

4.06 ± 0.48

3.92 ± 0.51

3.99 ± 0.44

4.01 ± 0.39

4.36 ± 0.52

0.008

Hb, g/L

123.88 ± 14.19

120.43 ± 17.15

119.19 ± 16.2

121.47 ± 15.88

132.48 ± 17.49

0.007

D-dimer, mg/L FEU

1.39 ± 1.41

1.89 ± 1.46

1.37 ± 1.5

1.44 ± 1.33

1.11 ± 2.29

0.119

CK-MB, ng/ml

59.1 (11.74, 158.55)

34.7 (6.41, 132.2)

42.21 (5.29, 139.66)

48.18 (7.25, 151.77)

19.54 (4.07, 79.41)

0.009

CTnI, ng/ml

32.55 (6.71, 59.7)

8.49 (5.47, 31.86)

11.23 (4.78, 36.7)

22.61 (6.17, 44.42)

9.18 (2.73, 38.22)

0.014

LDL, mmol/L

2.5 ± 0.95

2.72 ± 0.81

2.52 ± 0.82

2.55 ± 0.95

2.57 ± 0.88

0.933

SCR, umol/L

100.48 ± 51.82

118.63 ± 44.29

104.22 ± 48.9

104.4 ± 48.7

91.4 ± 50.6

0.217

eGFR, ml/min/1.73 m2

69.01 ± 30.18

53.23 ± 21.42

62.31 ± 26.4

62.89 ± 25.3

82.37 ± 31.1

0.001

SUA, umol/L

329.8 ± 75.42

384.73 ± 97.18

352.41 ± 79.3

346.39 ± 85.75

337.1 ± 97.28

0.525

ABO

      

 A, n (%)

21 (52.5)

6 (40)

3 (50)

30 (49.18)

213 (35.5)

0.012

 B, n (%)

11 (27.5)

5 (33.33)

2 (33.33)

18 (29.51)

227 (37.83)

0.213

 O, n (%)

6 (15)

3 (20)

1 (16.67)

10 (16.39)

116 (19.33)

0.775

 AB, n (%)

2 (5)

1 (6.67)

0 (0)

3 (4.92)

44 (7.33)

0.841

LVEDd, mm

48.3 ± 9.49

49.2 ± 7.08

48.41 ± 7.48

48.55 ± 8.91

48.36 ± 5.1

0.803

LVESd, mm

38.27 ± 10.16

36.76 ± 8.24

37.01 ± 8.79

37.47 ± 9.7

35.76 ± 7.12

0.389

LVEF (%)

48.12 ± 9.29

48.15 ± 10.57

47.78 ± 8.82

48.14 ± 10.28

58.19 ± 9.92

< 0.001

GRACE RS

197.29 ± 39.41

211.22 ± 40.19

201.4 ± 38.52

200.12 ± 41.73

161 ± 31.5

< 0.001

Primary PCI treatment, n (%)

14 (35)

4 (26.67)

3 (50)

21 (34.43)

416 (69.33)

< 0.001

In-hospital mortality, n (%)

38 (95)

10 (66.67)

2 (33.33)

50 (81.97)

25 (4.17)

< 0.001

  1. Data are number (%), mean (SD), or median (IQR)
  2. FWR, free wall rupture; VSR, ventricular septal rupture; PMR, papillary muscle rupture; HT, hypertension; DM, diabetes mellitus; CHF, chronic heart failure; TIA, transient ischemic attack; MI, myocardial infarction; CAD, coronary artery disease; PCI, percutaneous coronary intervention; CABG, coronary artery bypass grafting; AF, atrial fibrillation; BMI, body mass index; STEMI, ST-segment elevation myocardial infarction; SBP, systolic blood pressure; β-RB, β-receptor blocker; ACEI, angiotensin-converting enzyme inhibitor; ARB, agiotensin Receptor Blocker; ESR, erythrocyte sedimentation rate; HBA1C. glycosylated hemoglobin; BNP, brain natriuretic peptide; WBC, white blood cell; RBC, red blood cell; Hb, haemoglobin; CK-MB, creatine kinase MB; CTnI, cardiac troponin I; LDL-C, low-density lipoprotein cholesterol; SCR, serum creatinine; eGFR, estimated glomerular filtration rate; SUA, serum uric acid; LVEDd, left ventricular end-diastolic dimension; LVESd, left ventricular end- systolic dimension; LVEF, left ventricular ejection fraction; GRACE RS, The Global Registry of Acute Coronary Events risk score; pPCI, primary percutaneous coronary intervention