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Table 2 Calculated parameters at baseline in patients with and without hypernatremia

From: Tolvaptan-induced hypernatremia related to low serum potassium level accompanying high blood pressure in patients with acute decompensated heart failure

 

With hypernatremia

Without hypernatremia

p value

BUN/Cr

19.2 ± 7.6

22.5 ± 7.7

0.074

PAC/PRA

144 ± 144

142 ± 158

0.969

C-serum osmolality, mOsm/L

304 ± 7

298 ± 10

0.012

U-Osm/S-Osm

1.5 ± 0.6

1.5 ± 0.7

0.838

FENa, %

2.3 ± 2.5

3.3 ± 4.8

0.434

FEUN, %

36.8 ± 12.9

34.8 ± 12.6

0.623

FEK, %

18.1 ± 18.3

15.1 ± 10.4

0.442

TTKG

4.3 ± 1.7

4.3 ± 2.0

0.995

  1. C-Serum osmolality = 2 × Na + BUN/2.8 + blood sugar/18; FENa = (U-Na × S-Cr)/(U-Cr × S-Na) × 100; FEUN = (U-UN × S-Cr)/(U-Cr × S-UN) × 100; FEK = (U-K × S-Cr)/(U-Cr × S-K) × 100; TTKG = {U-K/(U-Osm/S-Osm)}/S-K
  2. U- urine-, S- serum-, C- calculated, BUN/Cr ratio of blood urea nitrogen to serum creatinine, PAC/PRA ratio of plasma aldosterone concentration to plasma renin activity, U-Osm/S-Osm ratio of urine osmolality to serum osmolality, FENa fractional excretion of sodium, FEUN fractional excretion of urea nitrogen, FEK fractional excretion of potassium, TTKG trans-tubular K gradient
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BMC Cardiovascular Disorders

ISSN: 1471-2261

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