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Table 1 Patient characteristics of the entire trial cohort and those stratified by CT CAD categories

From: Usefulness of preoperative coronary computed tomography angiography in high risk non-cardiovascular surgery old patients with unknown or suspected coronary artery disease

Variables Total cohort No CAD Nonobstructive CAD Obstructive CAD p value
n = 841 n = 485 n = 192 n = 164 n = 841
Age (years) 69.5 ± 5.8 68.4 ± 5.5 70.6 ± 6.3 71.3 ± 5.4 < 0.001
Male 627 (74.6) 334 (68.9) 155 (80.7) 138 (84.1) < 0.001
Suspected CAD 70 (8.3) 28 (5.8) 15 (7.8) 27 (16.5) 0.001
Positive ECG 110 (13.1) 48 (10.0) 17 (8.9) 45 (27.4) < 0.001
HR (beats/min) 73.6 ± 25.7 74.0 ± 30.9 72.8 ± 17.2 73.3 ± 13.8 0.855
LVEF (%) 66.6 ± 7.1 66.5 ± 6.7 67.0 ± 6.9 66.4 ± 8.3 0.655
Median Agatston score   0 71 (17.4, 190.2) 348.4 (124.3, 789.9) < 0.001
Risk factors
 Smoking 401 (47.7) 210 (43.3) 100 (52.1) 91 (55.5) 0.003
 Diabetes mellitus 85 (10.1) 38 (7.8) 21 (10.9) 26 (15.9) 0.004
 Hypertension 293 (34.8) 138 (28.5) 73 (38.0) 82 (50.0) < 0.001
 Hyperlipidemia 248 (29.5) 137 (28.2) 57 (29.7) 54 (32.9) 0.272
 Stroke 26 (3.1) 12 (2.5) 5 (2.6) 9 (5.5) 0.101
Medication use at perioperative period
 Statins 80 (9.5) 16 (3.3) 11 (5.7) 53(32.3) < 0.001
 ACEi or ARB 66 (7.8) 27 (5.6) 17 (8.9) 22 (13.4) 0.001
Calcium channel blockers 195 (23.2) 91 (18.8) 52 (27.1) 52 (31.7) < 0.001
 Beta-blocker 124 (14.7) 53 (10.9) 26 (13.5) 45 (27.4) < 0.001
 Diuretics 288 (34.2) 148 (30.5) 81 (42.2) 59 (36.0) 0.06
 Nitrate agent 184 (21.9) 86 (17.7) 45 (23.4) 53 (32.3) < 0.001
  1. Unless otherwise indicated, values are mean ± standard deviations (SD) or n (%)
  2. CT computed tomography, CAD coronary artery disease, ECG electrocardiography, HR heart rate, LVEF left ventricular ejection fraction, ACEi angiotensin converting enzyme inhibitor, ARB angiotensin II receptor blocker
  3. p value represents comparison among no CAD, non-obstructive and obstructive CAD
  4. Data in parentheses are interquartile ranges