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Table 3 Sex-race: sequential models for the odds of elevated LDL cholesterol

From: Joint effect of race/ethnicity or location of residence and sex on low density lipoprotein-cholesterol among veterans with type 2 diabetes: a 10-year retrospective cohort study

 

LDL ≥ 100

LDL ≥ 70

Base model

Full model

Base model

Full model

Variable

n = 673,841

n = 636,985

n = 673,841

n = 636,985

 Annual visit (0 to 9)

0.93 (0.93, 0.93)

0.94 (0.94, 0.94)

0.87 (0.87, 0.87)

0.89 (0.89, 0.89)

Sex × race**

    

 Non-Hispanic white × male

Ref

Ref

Ref

Ref

 Non-Hispanic white × female

3.01 (2.84, 3.19)

2.59 (2.44, 2.77)

2.29 (2.16, 2.44)

2.06 (1.93, 2.20)

 Non-Hispanic black × male

1.80 (1.76, 1.84)

1.76 (1.72, 1.80)

1.57 (1.53, 1.60)

1.54 (1.51, 1.58)

 Non-Hispanic black × female

5.97 (5.05, 7.06)

5.38 (4.45, 6.51)

4.41 (3.66, 4.31)

3.93 (3.18, 4.87)

 Hispanic × male

1.31 (1.27, 1.34)

1.25 (1.21, 1.29)

1.15 (1.12, 1.18)

1.08 (1.05, 1.11)

 Hispanic × female

3.72 (2.68, 5.16)

2.56 (1.79, 3.66)

2.26 (1.60, 3.18)

1.83 (1.26, 2.64)

 Other race × male

1.15 (1.10, 1.21)

1.13 (1.08, 1.19)

1.02 (0.98, 1.06)

1.00 (0.95, 1.04)

 Other race × female

3.34 (2.45, 4.56)

2.98 (2.11, 4.22)

2.85 (2.04, 3.97)

2.58 (1.77, 3.76)

Location of residence

    

 Urban

 

Ref

 

Ref

 Rural

 

1.28 (1.26, 1.30)

 

1.23 (1.22, 1.25)

 Age (per year)

 

0.99 (0.99, 1.00)

 

0.99 (0.99, 0.99)

Marital status

    

 Married versus unmarried (ref.)

 

0.86 (0.84, 0.87)

 

0.94 (0.93, 0.96)

 Disability (> 50% service-related)

 

0.98 (0.96, 1.00)

 

0.98 (0.96, 0.99)

Smoking status

    

 Smoker versus non-smoker (ref.)

 

1.10 (1.08, 1.12)

 

1.01 (0.99, 1.03)

 Number primary care visits (per year)

 

0.99 (0.99, 0.99)

 

0.99 (0.99, 0.99)

A1C

    

 A1C > 8% (64 mmol/mol) versus A1C ≤ 8% (64 mmol/mol) (ref)

 

1.33 (1.32, 1.35)

 

1.20 (1.19, 1.22)

ASCVD

    

 Acute coronary syndr

 

1.09 (1.07, 1.11)

 

0.93 (0.92, 0.95)

 Atheroscl. cerebro. dis

 

1.14 (1.12, 1.19)

 

1.05 (1.03, 1.07)

 Coronary heart dis

 

0.59 (0.58, 0.60)

 

0.56 (0.55, 0.57)

 Peripheral artery dis

 

0.93 (0.92, 0.93)

 

0.89 (0.88, 0.90)

Statins prescribed

    

 No statin

 

Ref

 

Ref

 Low/moderate-intensity statin

 

0.34 (0.32, 0.36)

 

0.41 (0.38, 0.43)

 High-intensity statin

 

0.29 (0.27, 0.31)

 

0.29 (0.27, 0.31)

Dual VA-CMS status

    

 > 80% VA utilization

 

Ref

 

Ref

 50–80% VA utilization

 

1.00 (0.99, 1.02)

 

0.98 (0.96, 0.99)

 < 50% VA utilization

 

0.99 (0.98, 1.00)

 

0.93 (0.92, 0.94)

History of comorbidity

    

 Psychiatric disorder

 

1.16 (1.14, 1.18)

 

1.06 (1.03, 1.07)

 Depression

 

1.17 (1.15, 1.19)

 

1.08 (1.07, 1.10)

 Inter cluster correlation

0.56 (0.56, 0.56)

0.56 (0.56, 0.56)

0.56 (0.56, 0.56)

0.56 (0.56, 0.56)

  1. LDL measured in mg/dL. Data measured between 2007 and 2016. Odds ratios (95% confidence intervals) from logistic random-intercept models
  2. ASCVD atherosclerotic cardiovascular disease, CMS Centers for Medicare and Medicaid, LDL low-density lipoprotein cholesterol, VA Veterans Affairs
  3. **p < 0.001