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Table 2 Comparison of glycaemic parameters, lipid profile and lipid risk factors and other biochemical parameters between control group (participants without diabetes) and diabetes group (patients with diabetes)

From: Increased osteoprotegerin level is associated with impaired cardiovagal modulation in type-2 diabetic patients treated with oral antidiabetic drugs

 

Control Group

Diabetes Group

(n = 42)

(n = 42)

Glycemic parameters

 FSG (mg/dL)

84.95 ± 14.86

162.74 ± 75.27***

 Insulin (μU/mL)

3.31 ± 1.27

6.76 ± 3.96 ΨΨΨ

 HOMA-IR

0.72 ± 0.41

3.17 ± 3.04 ΨΨΨ

Lipid profile

 TC (mg/dL)

193.02 ± 38.86

175.93 ± 35.45

 HDL-C (mg/dL)

42.88 ± 9.31

43.54 ± 9.87

 LDL-C (mg/dL)

131.10 ± 31.53

103.60 ± 38.35**

 TG (mg/dL)

113.21 ± 84.13

144.45 ± 69.27 ΨΨΨ

 VLDL-C (mg/dL)

22.64 ± 16.82

28.88 ± 13.86 ΨΨΨ

Lipid risk factors

 Non HDL-C (mg/dL)

150.14 ± 38.26

132.38 ± 36.23

 TG/HDL-C

2.78 ± 2.11

3.78 ± 2.92 Ψ

 TC/HDL-C

4.67 ± 1.21

4.26 ± 1.33

 LDL-C/HDL-C

3.18 ± 0.95

2.52 ± 1.18*

 AIP

0.35 ± 0.27

0.48 ± 0.27*

Inflammatory markers

 hsCRP (mg/L)

0.72 ± 0.38

1.09 ± 1.31Ψ

 Osteoprotegerin (pg/mL)

131.20 ± 73.66

225.54 ± 128.78 ***

  1. The values are expressed as Mean ± SD
  2. FSG fasting serum glucose, HOMA-IR homeostatic model assessment of insulin resistance, TC total choleterol, HDL-C high density cholesterol, LDL-C low density cholesterol, TG triglyceride, VLDL-C very low density cholesterol, Non HDL-C non HDL cholesterol, AIP atherogenic index of plasma = log10[TG/HDL-C], hsCRP high-sensitive C-reactive protien
  3. *p < 0.05; **p < 0.01;***p < 0.001 by Student’s unpaired ‘t’ test
  4. Ψp < 0.05; ΨΨΨp < 0.001 by Mann Whitney U test