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Table 2 Comparison of demographic, preoperative, intraoperative, and postoperative characteristics between patients with AKI and those without AKI

From: Intraoperative blood transfusion volume is an independent risk factor for postoperative acute kidney injury in type A acute aortic dissection

  No AKI Stage 1 AKI Stage 2 or 3 AKI P value
N 48 31 51
Age (years), mean (SD) 53.15 (11.61) 57.13 (11.22) 54.78 (12.39) 0.35
Male, n (%) 33 (68.75%) 27 (87.10%) 41 (80.39%) 0.16
Hypertension, n (%) 22 (45.83%) 25 (80.65%) 34 (66.67%) 0.006
Diabetes mellitus, n (%) 1 (2.08%) 3 (9.68%) 4 (7.84%) 0.37
COPD, n (%) 2 (4.17%) 1 (3.23%) 3 (5.88%) 1.00
Stroke, n (%) 3 (6.25%) 2 (6.45%) 3 (5.88%) 1.00
Coronary artery disease, n (%) 1 (2.08%) 4 (12.90%) 2 (3.92%) 0.12
SBP (mmHg), mean (SD) 131.90 (22.70) 125.39 (27.54) 140.27 (32.43) 0.06
DBP (mmHg), mean (SD) 71.02 (16.53) 66.71 (21.57) 78.49 (19.15) 0.018
eGFR [ml/(min.1.73m2)], mean (SD) 100.57 (30.65) 71.53 (22.21) 94.84 (51.22) 0.007
Preoperative hemoglobin (g/l), mean (SD) 125.87 (18.39) 120.77 (22.74) 124.53 (22.44) 0.61
Emergency operation, n (%) 21 (43.75%) 25 (80.65%) 42 (82.35%) < 0.001
CPB time (min), median (IQR) 176 (120–221) 173 (132–212) 210 (185–244) 0.001
Aortic cross clamp time (min), median (IQR) 96 (76–118) 96 (74–107) 120 (95–127) 0.004
Circulatory arrest time (min), median (IQR) 12 (0–20) 15 (0–24) 18 (8–24) 0.26
Nasopharyngeal temperature (°C), mean (SD) 20.9 (2.1) 20.8 (2.1) 20.4 (2.5) > 0.05
Total arch replacement, n (%) 20 (41.67%) 18 (58.06%) 38 (74.51%) 0.004
Semi-arch replacement, n (%) 2 (4.17%) 1 (3.23%) 0 (0.00%) 0.35
Stented elephant trunk, n (%) 19 (39.58%) 17 (54.84%) 36 (70.59%) 0.008
Bentall procedure, n (%) 27 (56.25%) 14 (45.16%) 14 (27.45%) 0.014
Ascending aorta replacement, n (%) 21 (43.75%) 17 (54.84%) 35 (68.63%) 0.044
Intraoperative erythrocytes use (ml), median (IQR) 1750 (1050–3375) 2200 (1400–2775) 2950 (1950–4350) 0.007
Intraoperative fresh frozen plasma use (ml), median (IQR) 850 (550–1200) 1000 (575–1550) 1000 (550–1925) 0.55
Intraoperative platelets use (ml), median (IQR) 600 (300–1200) 1200 (900–1200) 1200 (750–1200) 0.006
Intraoperative cryoprecipitate use (ml), median (IQR) 350 (0–500) 475 (250–525) 500 (250–560) 0.11
Intraoperative blood transfusion(ml), median (IQR) 2825 (1988–5538) 4400 (2750–5800) 4850 (3650–6875) 0.007
ARDS, n (%) 8 (16.67%) 13 (41.94%) 31 (60.78%) < 0.001
Perioperative myocardial infarction, n (%) 0 (0.00%) 0 (0.00%) 2 (3.92%) 0.342
Redo surgery, n (%) 2 (4.17%) 3 (9.68%) 13 (25.49%) 0.007
Length of ICU (day), median (IQR) 4.00 (2.75–5.25) 6.00 (3.50–6.50) 9.00 (3.00–14.50) 0.001
Length of mechanical ventilation (day), median (IQR) 2.00 (1.00–3.00) 2.00 (1.00–4.00) 5.00 (2.00–7.50) < 0.001
In-hospital mortality, n (%) 2 (4.17%) 5 (16.13%) 14 (27.45%) 0.005
  1. AKI, acute kidney injury; ARDS, adult respiratory distress syndrome; COPD, chronic obstructive pulmonary; CPB, cardiopulmonary bypass; DBP, diastolic blood pressure; eGFR, estimated glomerular filtration rate; ICU, intensive care unit; SD, standard deviation; SBP, systolic blood pressure