Significant functional tricuspid regurgitation portends poor outcomes in patients with atrial fibrillation and preserved left ventricular ejection fraction

Table 4 Univariate and multivariable analyses of the predictors of death and heart failure

Factors	Univariate analysis			Multivariable analysis
Factors	HR	95%CI	P-value	HR	95%CI	P-value
Age	1.03	1.01–1.06	0.013
Female gender	3.53	1.94–6.42	< 0.001
CHA₂DS₂-VASc score	1.50	1.29–1.75	< 0.001	1.47	1.25–1.73	< 0.001
History of stroke	2.49	1.47–4.19	0.001
History of heart failure	2.04	1.13–3.68	0.019
Diuretics	3.56	2.11–6.02	< 0.001	2.29	1.34–3.92	0.003
LAV index	1.02	1.01–1.03	0.005
Significant FTR	4.78	2.84–8.05	< 0.001	3.62	2.11–6.21	< 0.001
Impaired RV systolic function	2.20	1.22–3.98	0.009
Pulmonary hypertension	2.68	1.59–4.51	< 0.001	2.10	1.22–3.60	0.007

Abbreviations: CI confidence interval, FTR functional tricuspid regurgitation, LAV left atrial volume, RV right ventricular, HR Hazard ratio

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