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Table 1 Baseline characteristics of ACS patients and controls

From: Correlation of serum N-Acetylneuraminic acid with the risk and prognosis of acute coronary syndrome: a prospective cohort study

  UAP (n = 537) MI (n = 100) Control (n = 129) F or χ2 p
Age (years) 64.96 ± 10.13 63.44 ± 10.51 57.43 ± 9.67* 28.960 0.000
Male (n, %) 299 (56) 78 (78) 51 (40) 33.833 0.000
Smoker (n, %) 89 (17) 21 (21) 13 (10)* 11.350 0.003
Hypertension (n, %) 300 (56) 67 (67) 63 (49)* 7.60 0.022
DM (n, %) 144 (27) 24 (24) 12 (9)* 17.763 0.000
AF (n, %) 21 (4) 5 (5) 6 (5) 0.337 0.845
Previous stroke (n, %) 49 (9) 6 (6) 9 (7) 1.460 0.482
FBG (mmol/L) 5.11 (4.54, 6.48) 5.96 (4.90, 8.23)** 4.95 (4.51, 5.75) 18.746 < 0.001
TC (mmol/L) 3.72 (3.03, 4.64) 3.50 (2.79, 5.01) 3.83 (3.08, 4.53) 0.363 0.834
TG (mmol/L) 1.34 (0.96, 1.94) 1.54 (1.02, 2.01)** 1.23 (0.86, 1.86) 6.807 0.003
HDL-C (mmol/L) 0.90 (0.75, 1.06) 0.83 (0.67, 1.00) 0.95 (0.79, 1.14)* 13.958 0.001
LDL-C (mmol/L) 2.01 (1.54, 2.62) 1.98 (1.39, 2.86) 2.08 (1.57, 2.56) 0.173 0.917
CRP (mg/L) 1.20 (0.50, 3.60) 2.30 (0.05, 6.18) 1.20 (0.60, 3.30) 1.158 0.560
UA (μmol/L) 301 (251, 364) 317 (258, 398)** 282 (243, 353) 8.223 0.016
SCr (μmol/L) 67 (60.5, 72) 70 (63.25, 86) 63 (56.5, 69) 34.574 < 0.001
D-dimer (mg/L) 0.27 (0.19, 0.45) 0.29 (0.19, 0.45) 0.23 (0.11, 0.39) 8.729 0.013
Lp(a) (mg/L) 225 (93.75, 387.75) 237 (90, 470) 217 (110, 453) 0.143 0.931
Neu5Ac (ng/ml) 227 (114, 312) 297 (220, 374) ** 207 (114, 276) 17.505 < 0.001
Coronary lesions (n, %)
 Three vessels 205 (30) 56 (37)** 11.075 0.001
 Two vessels 194 (26) 27 (23) 3.099 0.078
 Single vessel 138 (44) 17 (40) 3.464 0.063
Gensini score 30.70 ± 28.61 53.04 ± 35.96** 6.876 0.000
CK-MB (U/L) 12.20 (0.00, 17.00) 40.62 (8.00, 42.00) ** 9.49 (0.00, 14.00) 35.032 < 0.001
TnI (μg/L) 0.37 (0.00, 0.19) 4.28 (0.07, 3.76) ** 0.36 (0.00, 0.35) 34.817 < 0.001
  1. *, p < 0.05 compared to MI patients;
  2. *, p < 0.05 compared to UAP patients;
  3. UAP Unstable angina pectoris, MI Myocardial infarction, DM Diabetes mellitus, AF Atrial fibrillation, FBG Fasting blood glucose, TC Total cholesterol, TG Triglyceride, HDL-C High-density lipoprotein cholesterol, LDL-C Low-density lipoprotein cholesterol, CRP C-reactive protein, UA Uric acid, SCr Serum creatinine, Lp(a) Lipoprotein (a), Neu5Ac N-acetylneuraminic acid, CK-MB MB isoform of creatine kinase, TnI Troponin I