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Table 1 Baseline characteristics of ACS patients and controls

From: Correlation of serum N-Acetylneuraminic acid with the risk and prognosis of acute coronary syndrome: a prospective cohort study

 

UAP (n = 537)

MI (n = 100)

Control (n = 129)

F or χ2

p

Age (years)

64.96 ± 10.13

63.44 ± 10.51

57.43 ± 9.67*

28.960

0.000

Male (n, %)

299 (56)

78 (78)

51 (40)

33.833

0.000

Smoker (n, %)

89 (17)

21 (21)

13 (10)*

11.350

0.003

Hypertension (n, %)

300 (56)

67 (67)

63 (49)*

7.60

0.022

DM (n, %)

144 (27)

24 (24)

12 (9)*

17.763

0.000

AF (n, %)

21 (4)

5 (5)

6 (5)

0.337

0.845

Previous stroke (n, %)

49 (9)

6 (6)

9 (7)

1.460

0.482

FBG (mmol/L)

5.11 (4.54, 6.48)

5.96 (4.90, 8.23)**

4.95 (4.51, 5.75)

18.746

< 0.001

TC (mmol/L)

3.72 (3.03, 4.64)

3.50 (2.79, 5.01)

3.83 (3.08, 4.53)

0.363

0.834

TG (mmol/L)

1.34 (0.96, 1.94)

1.54 (1.02, 2.01)**

1.23 (0.86, 1.86)

6.807

0.003

HDL-C (mmol/L)

0.90 (0.75, 1.06)

0.83 (0.67, 1.00)

0.95 (0.79, 1.14)*

13.958

0.001

LDL-C (mmol/L)

2.01 (1.54, 2.62)

1.98 (1.39, 2.86)

2.08 (1.57, 2.56)

0.173

0.917

CRP (mg/L)

1.20 (0.50, 3.60)

2.30 (0.05, 6.18)

1.20 (0.60, 3.30)

1.158

0.560

UA (μmol/L)

301 (251, 364)

317 (258, 398)**

282 (243, 353)

8.223

0.016

SCr (μmol/L)

67 (60.5, 72)

70 (63.25, 86)

63 (56.5, 69)

34.574

< 0.001

D-dimer (mg/L)

0.27 (0.19, 0.45)

0.29 (0.19, 0.45)

0.23 (0.11, 0.39)

8.729

0.013

Lp(a) (mg/L)

225 (93.75, 387.75)

237 (90, 470)

217 (110, 453)

0.143

0.931

Neu5Ac (ng/ml)

227 (114, 312)

297 (220, 374) **

207 (114, 276)

17.505

< 0.001

Coronary lesions (n, %)

 Three vessels

205 (30)

56 (37)**

–

11.075

0.001

 Two vessels

194 (26)

27 (23)

–

3.099

0.078

 Single vessel

138 (44)

17 (40)

–

3.464

0.063

Gensini score

30.70 ± 28.61

53.04 ± 35.96**

–

6.876

0.000

CK-MB (U/L)

12.20 (0.00, 17.00)

40.62 (8.00, 42.00) **

9.49 (0.00, 14.00)

35.032

< 0.001

TnI (μg/L)

0.37 (0.00, 0.19)

4.28 (0.07, 3.76) **

0.36 (0.00, 0.35)

34.817

< 0.001

  1. *, p < 0.05 compared to MI patients;
  2. *, p < 0.05 compared to UAP patients;
  3. UAP Unstable angina pectoris, MI Myocardial infarction, DM Diabetes mellitus, AF Atrial fibrillation, FBG Fasting blood glucose, TC Total cholesterol, TG Triglyceride, HDL-C High-density lipoprotein cholesterol, LDL-C Low-density lipoprotein cholesterol, CRP C-reactive protein, UA Uric acid, SCr Serum creatinine, Lp(a) Lipoprotein (a), Neu5Ac N-acetylneuraminic acid, CK-MB MB isoform of creatine kinase, TnI Troponin I