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Table 4 Univariate regression analysis of possible predictors for aortic AIx (AP/PP) normalized for a heart rate of 75/min in all study subjects (n = 122)

From: Increased augmentation index in patients with Ehlers-Danlos syndrome

Variable

Coefficient

95% Confidence Interval

p-value

Age, years

0.43

0.27 to 0.59

< 0.001

Male sex, (yes/no)

−13.36

−17.96 to −8.76

< 0.001

Height, cm

−0.61

−0.80 to −0.42

< 0.001

Weight, kg

−0.21

− 0.36 to − 0.06

0.007

BMI, kg/m2

0.19

−0.40 to 0.78

0.532

Ehlers-Danlos Syndrome, (yes/no)

8.10

3.59 to 12.60

0.001

Mean systolic blood pressure, mmHg

0.124

−0.05 to 0.30

0.168

Mean diastolic blood pressure, mmHg

0.42

0.22 to 0.61

< 0.001

Smoking, (yes/no)

2.78

−3.18 to 8.79

0.357

Pack years of smoking, n

0.41

0.12 to 0.69

0.006

Antihypertensive Drugs, (yes/no)

8.67

0.55 to 16.79

0.037

Antiplatelet Drugs, (yes/no)

−5.88

−32.13 to 20.37

0.658

NSAID, (yes/no)

7.03

−0.07 to 14.19

0.052

  1. AIx Augmentation index; BMI Body-Mass-Index; NSAID non-steroidal anti-inflammatory drugs