Table 4 Differences in the age of the first episode MI among patients with 0, 1 and ≥ 2 affected relatives with the history of premature CVD events and CVD events at any age
Number of relatives: | 0 | 1 | ≥2 | 0 vs 1 Delta [95% CI] | 0 vs ≥2 Delta [95% CI] |
|---|---|---|---|---|---|
Family history of premature CVD events | |||||
Patients with first-degree relatives affected years ±SD (n) | 56.6 ± 15.3 (n = 363) | 48.6 ± 11.1 (n = 92) | 41.8 ± 5.9 (n = 10) | 8.0 [4.0–12.0] | 14.8 [4.0–25.7] |
p | < 0.0001 | < 0.0001 | |||
Patients with first- and second degree relatives affected years ±SD (n) | 56.5 ± 15.3 (n = 344) | 50.7 ± 12.6 (n = 87) | 47.0 ± 10.9 (n = 32) | 5.8 [1.7–9.9] | 9.5 [3.2–15.7] |
p | 0.0003 | < 0.0001 | |||
Family history of CVD events at every age | |||||
Patients with first-degree relatives affected years ±SD (n) | 57.9 ± 15.7 (n = 239) | 51.9 ± 13.5 (n = 184) | 47.9 ± 10.1 (n-40) | 6.0 [2.7–9.3] | 10.0 [4.2–15.8] |
p | < 0.0001 | < 0.0001 | |||
Patients with first- and second degree relatives affected years ±SD (n) | 58.1 ± 15.7 (n = 201) | 52.5 ± 13.5 (n = 183) | 50.9 ± 13.6 (n = 79) | 5.6 [2.1–9.1] | 7.1 [2.6–11.7] |
p | 0.0002 | 0.0005 | |||