Table 4 Differences in the age of the first episode MI among patients with 0, 1 and ≥ 2 affected relatives with the history of premature CVD events and CVD events at any age
| Number of relatives: | 0 | 1 | ≥2 |
0 vs 1 Delta [95% CI] |
0 vs ≥2 Delta [95% CI] |
|---|---|---|---|---|---|
| Family history of premature CVD events | |||||
|
Patients with first-degree relatives affected years ±SD (n) |
56.6 ± 15.3 (n = 363) |
48.6 ± 11.1 (n = 92) |
41.8 ± 5.9 (n = 10) | 8.0 [4.0–12.0] | 14.8 [4.0–25.7] |
| p | < 0.0001 | < 0.0001 | |||
|
Patients with first- and second degree relatives affected years ±SD (n) |
56.5 ± 15.3 (n = 344) |
50.7 ± 12.6 (n = 87) |
47.0 ± 10.9 (n = 32) | 5.8 [1.7–9.9] | 9.5 [3.2–15.7] |
| p | 0.0003 | < 0.0001 | |||
| Family history of CVD events at every age | |||||
|
Patients with first-degree relatives affected years ±SD (n) |
57.9 ± 15.7 (n = 239) |
51.9 ± 13.5 (n = 184) |
47.9 ± 10.1 (n-40) | 6.0 [2.7–9.3] | 10.0 [4.2–15.8] |
| p | < 0.0001 | < 0.0001 | |||
|
Patients with first- and second degree relatives affected years ±SD (n) |
58.1 ± 15.7 (n = 201) |
52.5 ± 13.5 (n = 183) |
50.9 ± 13.6 (n = 79) | 5.6 [2.1–9.1] | 7.1 [2.6–11.7] |
| p | 0.0002 | 0.0005 | |||