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Table 4 Differences in the age of the first episode MI among patients with 0, 1 and ≥ 2 affected relatives with the history of premature CVD events and CVD events at any age

From: Younger age of patients with myocardial infarction is associated with a higher number of relatives with a history of premature atherosclerosis

Number of relatives: 0 1 ≥2 0 vs 1
Delta [95% CI]
0 vs ≥2
Delta [95% CI]
Family history of premature CVD events
 Patients with first-degree relatives affected
years ±SD (n)
56.6 ± 15.3
(n = 363)
48.6 ± 11.1
(n = 92)
41.8 ± 5.9
(n = 10)
8.0 [4.0–12.0] 14.8 [4.0–25.7]
p     < 0.0001 < 0.0001
Patients with first- and second degree relatives affected
years ±SD (n)
56.5 ± 15.3
(n = 344)
50.7 ± 12.6
(n = 87)
47.0 ± 10.9
(n = 32)
5.8 [1.7–9.9] 9.5 [3.2–15.7]
p     0.0003 < 0.0001
Family history of CVD events at every age
Patients with first-degree relatives affected
years ±SD (n)
57.9 ± 15.7
(n = 239)
51.9 ± 13.5
(n = 184)
47.9 ± 10.1
(n-40)
6.0 [2.7–9.3] 10.0 [4.2–15.8]
p     < 0.0001 < 0.0001
Patients with first- and second degree relatives affected
years ±SD (n)
58.1 ± 15.7
(n = 201)
52.5 ± 13.5
(n = 183)
50.9 ± 13.6
(n = 79)
5.6 [2.1–9.1] 7.1 [2.6–11.7]
p     0.0002 0.0005