Fig. 1

Differences among the MI < 50, MI ≥ 50 and no-MI < 50 groups in the percentage of cases with 0, 1 or ≥ 2 first- and second-degree relatives with a history of CVD events: a family history of premature CVD events with ≥2 affected relatives: 10.8% cases in the MI < 50 group vs 2.9% cases in the MI ≥50 group (p < 0.0001) and 10.8% cases in the MI < 50 group vs 3.7% cases in the no-MI < 50 group (p < 0.0001); b family history of CVD events with ≥2 affected relatives at every age: 21.4% cases in the MI < 50 group vs 12.7% cases in the MI ≥50 group (p < 0.0001) and 21.4% cases in the MI < 50 group vs 10.8% cases in the no-MI < 50 group (p < 0.0001)