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Table 2 General characteristics of patients by tertiles of TMAO levels

From: Plasma trimethylamine n-oxide is associated with renal function in patients with heart failure with preserved ejection fraction

 

Tertiles of circulating TMAO

 

Tertile 1

Tertile 2

Tertile 3

p

(<  9.7 μg/l) n = 108

(9.7–15.58 μg/l) n = 109

(>  15.58 μg/l) n = 107

Male (n, %)

58 (53.7%)

70 (64.22)

72 (66.67)

0.1

Age (years)

58 ± 1

61 ± 1

62 ± 1

< 0.01

Height (cm)

162 ± 1

163 ± 1

164 ± 1

0.38

Weight (kg)

64 ± 1

67 ± 1

66 ± 1

0.36

BMI (kg/m2)

24 ± 0

25 ± 0

24 ± 0

0.77

SBP (mmHg)

131 ± 3

129 ± 2

133 ± 2

0.06

DBP (mmHg)

77 ± 1

76 ± 1

77 ± 1

0.57

HR (bpm)

72 ± 1

72 ± 1

72 ± 1

0.91

Glu (mmol/l)

5.2 (4.72–5.93)

5.34 (4.85–5.93)

5.42 (4.88–5.92)

0.38

HbA1c (%)

5.7 (5.5–6.1)

6.1 (5.7–6.1)

6.1 (5.9–6.5)

0.03

Cr (μmol/l)

83.1 (71.1–94)

90.5 (82.05–101.4)

97 (82.1–118.5)

< 0.01

eGFR (ml/min/1.73m2)

61.77 (53.16–73.68)

56.22 (49.27–65.64)

51.55 (39.72–62.32)

< 0.01

TG (mmol/l)

1.56 (1.06–2.18)

1.48 (0.98–2.09)

1.65 (1.36–2.73)

0.14

TC (mmol/l)

4.15 (3.64–5.48)

4.2 (3.57–5.18)

4.28 (3.65–5.23)

0.5

HDL (mmol/l)

1.19 (0.97–1.48)

1.1 (0.87–1.34)

1.01 (0.87–1.19)

0.05

LDL (mmol/l)

2.66 (2.04–3.42)

2.61 (2.25–3.24)

2.76 (2.22–3.45)

0.25

ALT (U/l)

21.7 (15.9–34)

22.5 (15.2–34.2)

24.2 (17.5–36.9)

0.6

AST (U/l)

22.2 (18.8–29.08)

22.7 (19.4–29.7)

23.5 (19–30.8)

0.51

WBC (109/l)

6.4 (5.33–7.78)

6.6 (5.2–8)

6.5 (5.3–7.7)

0.3

CK-MB (U/l)

16.6 (12.1–21.9)

17.2 (12.1–25.45)

16.4 (13.1–22.6)

0.2

EF%

59 (57–65)

57 (54–64)

57 (55–64)

0.6

HFpEF (n, %)

64 (59.26%)

80 (73.39%)

84 (78.5%)

< 0.01

  1. Continuous data are presented as mean ± SD or median (interquartile range), and categorical variables are presented as counts and percentage (%)