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Table 1 Baseline characteristics of subjects stratified by CON and HFpEF

From: Plasma trimethylamine n-oxide is associated with renal function in patients with heart failure with preserved ejection fraction

 

CON (n = 96)

HFpEF (n = 228)

p

Male (n, %)

57 (59.38%)

143 (62.72%)

0.6

Age (years)

56 ± 1

62 ± 1

< 0.01

Height (cm)

163 ± 1

162 ± 0

0.67

Weight (kg)

65 ± 1

66 ± 1

0.76

BMI (kg/m2)

24 ± 0

25 ± 0

0.57

SBP (mmHg)

127 ± 2

135 ± 1

< 0.01

DBP (mmHg)

76 ± 1

77 ± 1

0.14

HR (bpm)

71 ± 1

72 ± 1

0.71

Glu (mmol/l)

5 (4.68–5.53)

5.42 (4.87–6.11)

< 0.01

HbA1c (%)

5.7 (5.5–5.7)

6.1 (5.9–6.2)

< 0.01

Cr (μmol/l)

82.6 (74.3–95.75)

91.95 (78.85–103.8)

< 0.01

eGFR (ml/min/1.73m2)

62.03 (52.64–70.74)

54.85 (46.57–64.26)

< 0.01

TG (mmol/l)

1.35 (1–1.8)

1.69 (1.13–2.48)

< 0.01

TC (mmol/l)

4.27 (3.63–4.89)

4.38 (3.65–5.38)

0.09

HDL (mmol/l)

1.12 (0.94–1.43)

1.04 (0.87–1.22)

0.01

LDL (mmol/l)

2.55 (2.04–3.01)

2.72 (2.22–3.49)

< 0.01

ALT (U/l)

21.3 (16.3–31.68)

24.2 (15.7–36.73)

0.5

AST (U/l)

22 (19.11–26.65)

23.45 (18.98–30)

0.35

WBC (109/l)

6.1 (5–7.53)

6.8 (5.5–7.8)

< 0.01

CK-MB (U/l)

16.45 (13.13–21.65)

15.3 (11.8–22.5)

0.3

EF (%)

61 (57–67)

59 (55–63)

0.35

TMAO (μg/l)

10.85 (6.35–15.58)

12.65 (9.32–18.66)

< 0.01

  1. Continuous data are presented as mean ± SD or median (interquartile range), and categorical variables are presented as counts and percentage (%)