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Table 2 A hierarchical regression of serum UA predicting cognitive function in patients with CHF (n = 192)

From: The relationship between serum uric acid and cognitive function in patients with chronic heart failure

 

Cognitive function

β

95% CI

R2

ΔR2

P-value

 

Lower

Upper

   

Block 1

–

–

–

0.584

–

0.000**

Age

−0.353

− 0.474

− 0.231

  

0.000**

Gender

−0.101

−0.213

0.012

  

0.080

Educational level

0.297

0.188

0.406

  

0.000**

NYHA function class

−0.035

−0.145

0.076

  

0.536

LVEF

0.013

−0.100

0.125

  

0.825

BMI

0.070

−0.041

0.180

  

0.214

Hemoglobin

−0.084

−0.208

0.040

  

0.184

hs-CRP

−0.188

−0.292

− 0.084

  

0.000**

eGFR

−0.002

−0.111

0.107

  

0.967

Hypertension

−0.073

−0.177

0.032

  

0.171

Type 2 diabetes mellitus

−0.009

−0.108

0.090

  

0.852

Atrial fibrillation

−0.080

−0.190

0.030

  

0.154

SDS score

−0.261

−0.379

− 0.142

  

0.000**

Block 2

–

–

–

0.598

0.014

0.015*

Serum UA

−0.130

−0.235

− 0.025

  

0.015

  1. UA uric acid, CHF chronic heart failure, NYHA New York Heart Association, LVEF left ventricular fraction, BMI body mass index, hs-CRP hypersensitive C-reactive protein, eGFR estimated glomerular filtration rate, SDS self-rating depression scale
  2. β standardized coefficients, CI confidence interval
  3. * P < 0.05; ** P < 0.01
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BMC Cardiovascular Disorders

ISSN: 1471-2261

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