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Table 1 Characteristics of study participants from the Malmö Offspring Study, with means (95% CI), SD, median (IQR) and proportions

From: Patterns of urinary albumin and IgM associate with markers of vascular ageing in young to middle-aged individuals in the Malmö offspring study

  All subjects Urinary IgM excretion Urinary albumin excretion
n = 1531 Not detectable
n = 1263
Urinary IgM ≥ 10 ng/L
n = 76
Not detectable
n = 838
U-ACR ≥ 3.0 mg/mmol
n = 27
U-ACR
1.5–2.9
mg/mmol
n = 40
U-ACR
0.1–1.4
mg/mmol
n = 624
Age, years (95% CI) 39.7 (39.1–40.4), SD 13.4 39.2 (38.5–40.0), SD 13.2 40.3 (37.1–43.4), SD 13.9 41.5 (40.6–42.4), SD 13.1 46.2 (40.6–51.8), SD 13.4 40.3 (36.0–44.6), SD 13.4 37.1 (36.0–38.2), SD 13.3
Women, n (%) 791 (52) 649 (51) 45 (59) 457 (55) 13 (48) 25 (63) 295 (47)
Body mass index, kg/m2 (95% CI) 25.8 (25.6–26.1), SD 4.7 25.8 (25.5–26.0), SD 4.7 25.1 (24.1–26.2) SD 4.5 25.9 (25.6–25.2), SD 4.4 27.0 (24.9–29.1), SD 5.3 26.1 (24.4–27.7), SD 5.3 25.7 (25.3–26.1), SD 5.1
Smoking (current), n (%) 197 (13) 168 (13) 8 (11) 90 (11) 5 (19) 7 (18) 95 (15)
Smoking, current or previous, n (%) 527 (34) 442 (35) 24 (32) 285 (34) 14 (52) 14 (35) 213 (34)
Waist circumference, cm (95% CI) 89.5 (88.9–90.2), SD 13.8 89.5 (88.8–90.3), SD 13.9 87.8 (85.0–90.6), SD 12.2 89.5 (88.6–90.3), SD 13.1 96.0 (89.7–102.3), SD 16.2 90.1 (85.0–95.3), SD 16.2 89.4 (88.2–90.5), SD 14.4
Systolic blood pressure, mmHg (95% CI) 117.1 (116.4–117.8), SD 14.4 116.9 (116.1–117.7), SD 14.1 119.8 (116.1–123.5), SD 16.0 115.7 (114.8–116.6), SD 13.2 129.9 (122.0–137.7), SD 21.5 122.3 (115.4–129.3), SD 21.5 118.1 (116.9–119.2), SD 14.8
Diastolic blood pressure, mmHg (95% CI) 71.4 (70.9–71.8), SD 9.5 71.2 (70.7–71.8), SD 9.5 73.3 (70.8–75.8), SD 9.5 70.8 (70.2–71.4), SD 8.9 79.8 (75.1–84.4), SD 11.5 75.0 (71.0–79.1), SD 12.6 71.5 (70.7–72.3), SD 9.8
HbA1c, mmol/mol (IQR) 34 (IQR 31–36) 34 (IQR 31.5–37) 34 (IQR 31.5–39) 34 (IQR 32–37) 35 (IQR 31–39.5) 35 (IQR 31.5–39.5) 33 (IQR 31–36)
Total cholesterol, mmol/L (95% CI) 5.0 (4.9–5.0), SD 1.1 5.0 (4.9–5.0), SD 1.1 4.9 (4.7–5.2), SD 1.0 5.1 (5.0–5.1), SD 1.1 5.2 (4.8–5.6), SD 1.0 5.1 (4.8–5.4), SD 1.0 4.8 (4.7–4.9), SD 1.1
HDL cholesterol, mmol/L (95% CI) 1.62 (1.59–1.64), SD 0.48 1.62 (1.59–1.64), SD 0.48 1.64 (1.53–1.75), SD 0.49 1.66 (1.63–1.69), SD 0.48 1.61 (1.40–1.82), SD 0.54 1.60 (1.44–1.76), SD 0.51 1.57 (1.53–1.60), SD 0.48
LDL cholesterol, mmol/L (95% CI) 3.13 (3.08–3.17), SD 0.96 3.10 (3.05–3.16), SD 0.97 3.09 (2.89–3.28), SD 0.83 3.19 (3.12–3.25), SD 0.97 3.27 (2.95–3.60), SD 0.83 3.29 (2.95–3.62), SD 1.04 3.03 (2.95–3.10), SD 0.94
LDL/HDL (95% CI) 2.14 (2.09–2.19), SD 1.00 2.13 (2.07–2.18), SD 1.01 2.07 (1.86–2.28), SD 0.90 2.11 (2.05–2.18), SD 0.96 2.23 (1.92–2.53), SD 0.77 2.40 (1.95–2.86), SD 1.41 2.15 (2.06–2.23), SD 1.04
Triglycerides, mmol/L (95% CI) 0.9 (IQR 0.7–1.4) 0.9 (IQR 0.7–1.3) 1.0 (IQR 0.7–1.2) 0.9 (IQR 0.7–1.3) 1.2 (IQR 0.9–1.5) 1.0 (IQR 0.8–1.6) 0.9 (IQR 0.7–1.4)
Creatinine, μmol/L (95% CI) 79.5 (78.8–80.2), SD 14.1 79.5 (78.8–80.3) SD 14.2 78.4 (75.3–81.4) SD 13.2 79.7 (78.7–80.6), SD 14.1 79.3 (72.7–85.9), SD 16.7 73.7 (69.5–78.1, SD 13.9 79.6 (78.5–80.7), SD 13.9
eGFR, mL/min/
1.73 m2 (95% CI)
85.3 (84.9–85.7), SD 7.9 85.6 (85.2–86.1), SD 7.9 85.2 (83.3–87.0), SD 7.9 84.7 (84.1–85.3), SD 8.5 80.3 (75.7–84.9), SD 11.6 85.8 (83.8–87.7), SD 6.0 86.4 (85.8–86.9), SD 6.8
Hypertension, n (%) 230 (15) 182 (14) 11 (14) 107 (13) 10 (37) 10 (25) 103 (17)
Diabetes, n (%) 38 (2.4) 30 (2.3) 1 (1.3) 15 (1.7) 1 (3.4) 2 (5) 20 (3.2)
Lipid lowering medication, n (%) 31 (2.0) 24 (1.9) 1 (1.3) 19 (2.2) 1 (3.4) 0 (0) 11 (1.7)
Anti-hypertensive treatment, n (%) 70 (4.6) 51 (4.0) 4 (5.2) 36 (4.3) 4 (14.8) 3 (7.5) 27 (4.3)
- Thiazides, n (%) 8 (0.5) 5 (0.3) 1 (1.3) 4 (0.4) 0 (0) 0 (0) 4 (0.6%)
- Beta blockers, n
(%)
28 (1.8) 23 (1.8) 2 (2.6) 14 (1.7) 1 (3.4) 1 (2.5) 12 (1.9)
- RAAS-
 Blockers, n (%)
39 (2.5) 27 (2.1) 0 (0) 21 (2.5) 2 (6.9) 1 (2.5) 13 (2.1)
- Calcium
antagonists (%)
20 (1.3) 15 (1.1) 1 (1.3) 9 (1.1) 1 (3.4) 1 (2.5) 9 (1.4)
History of AMI (%) 12 (0.8) 10 (0.8) 0 (0) 5 (0.6) 0 (0) 0 (0) 7 (1.1)
History of stroke (%) 12 (0.8) 7 (0.6) 1 (1.3) 3 (0.4) 2 (6.8) 0 (0) 7 (1.1)
  1. AMI acute myocardial infarction, CI confidence interval, eGFR estimated glomerular filtration rate, IQR Interquartile range, RAAS renin-angiotensin-aldosterone system, U-ACR urinary albumin creatinine ratio