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Table 2 Risk factors associated with baPWV in mixed models

From: Platelet counts are associated with arterial stiffness in Chinese Han population: a longitudinal study

 

All

DM

Non-DM

beta (95%CI)

P value

beta (95%CI)

P value

beta (95%CI)

P value

Age (year)

12.69 (12.44,12.92)

< 0.001*

12.47 (12.20,12.74)

< 0.001*

14.64 (13.78,15.48)

< 0.001*

Postprandial 2 h-glucose (mmol/L)

10.46 (9.24,11.68)

< 0.001*

10.38 (8.71,12.05)

< 0.001*

6.42 (3.81,9.04)

< 0.001*

Systolic blood pressure (mmHg)

5.95 (5.93,6.18)

< 0.001*

5.98 (5.74,6.21)

< 0.001*

5.76 (5.14,6.38)

< 0.001*

Hypertension

NA

NA

25.80 (18.26,33.33)

< 0.001*

NA

NA

Platelet counts (109/L, per SD)

NA

NA

10.77 (5.91,20.63)

< 0.001*

NA

NA

Mean corpuscular volume (fL)

NA

NA

0.04(−0.53,0.61)

0.891

NA

NA

Coronary heart disease

NA

NA

−2.48(−14.03,9.07)

0.673

NA

NA

Interaction term: DM × PLTa

0.177 (0.067, 0.287)

0.0016*

NA

NA

NA

NA

  1. Only variables which were significantly associated with baPWV in lasso regression were included in mixed models
  2. aIn all participants, interaction terms of diabetes (DM) and platelet counts (PLT) were added in mixed models, adjusting for age, Postprandial 2 h-glucose, Systolic blood pressure
  3. *P value is significant after Bofferoni correction