Skip to main content

Table 2 Univariate- and multivariable Cox regression models applying continuous loge-transformed values of hs-cTnT, copeptin and NT-proBNP

From: N-terminal pro-B-type natriuretic peptide as a prognostic indicator for 30-day mortality following out-of-hospital cardiac arrest: a prospective observational study

 

Univariate

Multivariable

Model 1

Model 2

HR (95% CI)

P-value

HR (95% CI)

P-value

HR (95% CI)

P-value

Total population

 loge Hs-cTnT

0.99 (0.78–1.29)

0.99

0.87 (0.66–1.15)

0.34

0.90 (0.68–1.19)

0.46

 loge Copeptin

1.08 (0.84–1.39)

0.54

0.88 (0.65–1.20)

0.42

0.92 (0.66–1.28)

0.62

 loge NT-proBNP

1.86 (1.44–2.41)

<  0.001

0.96 (0.64–1.43)

0.84

0.88 (0.57–1.36)

0.57

Patients surviving to hospital admission

 loge Hs-cTnT

0.96 (0.67–1.38)

0.83

0.85 (0.58–1.25)

0.41

0.87 (0.61–1.26)

0.48

 loge Copeptin

1.40 (0.95–2.06)

0.093

1.20 (0.75–1.93)

0.45

1.07 (0.62–1.83)

0.81

 loge NT-proBNP

1.86 (1.24–2.78)

0.003

0.93 (0.50–1.73)

0.83

0.79 (0.41–1.49)

0.46

VF-patients

 loge Hs-cTnT

0.85 (0.59–1.24)

0.41

0.78 (0.52–1.17)

0.24

0.85 (0.56–1.28)

0.43

 loge Copeptin

1.15 (0.81–1.63)

0.44

1.01 (0.67–1.51)

0.98

0.95 (0.60–1.52)

0.85

 loge NT-proBNP

1.67 (1.07–2.60)

0.023

0.84 (0.43–1.64)

0.61

0.51 (0.22–1.19)

0.12

  1. Abbreviations: loge hs-cTnT loge-transformed value of hs-cTnT, loge Copeptin loge-transformed value of copeptin, loge NT-proBNP loge-transformed value of N-terminal pro B-type natriuretic peptide, VF ventricular fibrillation, HR hazard ratio, 95% CI 95% confidence interval. Model 1; multivariable model adjusting for age, loge-creatinine, first recorded heart rhythm and duration of resuscitation. Model 2; multivariable model adjusting for age, loge-creatinine, first recorded heart rhythm, duration of resuscitation, witnessed cardiac arrest and bystander-initiated cardiopulmonary resuscitation