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Table 2 Association of Non-genetic variables in the study subjects

From: Association of ESR1 (rs2234693 and rs9340799), CETP (rs708272), MTHFR (rs1801133 and rs2274976) and MS (rs185087) polymorphisms with Coronary Artery Disease (CAD)

Parameters

Patients (N = 400)

Controls (N = 400)

Odds Ratio

p-value

BMI

24.99 ± 5.75

23.21 ± 4.28

–

< 0.0001

WHR

0.99 ± 0.08

0.96 ± 0.13

–

0.008

Blood Pressure (mm Hg)

 Systolic BP (SBP)

142.90 ± 20.12

125.04 ± 8.30

–

< 0.0001*

 Diastolic BP (DBP)

89.17 ± 11.13

83.46 ± 8.48

–

< 0.0001*

 Pulse Pressure (PP)

53.73 ± 16.77

41.58 ± 8.12

–

< 0.0001*

 Pulse Rate (PR)

82.11 ± 12.23

74.41 ± 4.91

–

< 0.0001*

 Total Cholesterol (TC) (mg/dl)

172.75 ± 55.30

143.30 ± 27.87

–

< 0.0001*

 Triglycerides (TG) (mg/dl)

191.27 ± 68.39

166.57 ± 30.22

–

< 0.0001*

 HDL- C (mg/dl)

40.67 ± 7.71

44.88 ± 6.93

–

< 0.0001*

 LDL-C (mg/dl)

121.29 ± 61.56

112.42 ± 33.94

–

0.01*

 HDL/TC ratio

0.259 ± 0.10

0.327 ± 0.91

–

< 0.0001*

Smoking

 Smokers

159 (39.75%)

50 (12.5%)

4.62 (3.23–6.60)

< 0.0001*

 Non-smokers

241 (60.25%)

350 (87.5%)

Ref. (1)

–

Physical inactivity

 Yes

249 (62.25%)

163 (40.75%)

2.40 (1.80–3.18)

< 0.0001*

 No

151 (37.75%)

237 (59.25%)

Ref. (1)

–

Dwelling

 Urban

215 (53.75%)

158 (39.5%)

 

0.00005*

 Rural

185 (46.25%)

242 (60.5%)

  
  1. * Significant values
  2. Abbrevations: BMI Body Mass Index, WHR Waist Hip Ratio, HDL-C High Density Lipoprotein-Cholesterol, LDL-C Low Density Lipoprotein-Cholesterol