Table 1 Baseline characteristics of the ACS population stratified by low-density lipoprotein cholesterol (LDL-C) (LDL-C < 1.8 mmol/L, LDL-C ≥ 1.8 mmol/L, no measurement) given by number and percentage (N, %) if nothing else is indicated (1 January 2010–31 December 2015)
Variable | ACS population, N = 4377 | |||
|---|---|---|---|---|
N (%) | LDL-C (mmol/L) during index hospitalizationa | |||
Total | < 1.8 | ≥ 1.8 | No | |
Overall | 4377 | 322 (7.4) | 2718 (62.1) | 1337 (30.5) |
ACS at index date | ||||
AMI | 3891 (88.9) | 275 (85.4) | 2530 (93.1) | 1086 (81.2) |
UA + CAG | 486 (11.1) | 47 (14.6) | 188 (6.9) | 251 (18.8 |
Age, mean ± SD | 67.8 ± 13.6 | 70.4 ± 11.9 | 65.5 ± 13.4 | 71.8 ± 13.3 |
Age groups | ||||
< 40 | 73 (1.7) | 5 (1.6) | 58 (2.1) | 10 (0.7) |
40–49 | 366 (8.4) | 8 (2.5) | 295 (10.9) | 63 (4.7) |
50–59 | 775 (17.7) | 42 (13.0) | 558 (20.5) | 175 (13.1) |
60–69 | 1126 (25.7) | 88 (27.3) | 718 (26.4) | 320 (23.9) |
70–79 | 1067 (24.4) | 103 (32.0) | 622 (22.9) | 342 (25.6) |
≥ 80 | 970 (22.2) | 76 (23.6) | 467 (17.2) | 427 (31.9) |
Gender | ||||
Male | 2787 (63.7) | 219 (68.0) | 1816 (66.8) | 752 (56.2) |
Female | 1590 (36.3) | 103 (32.0) | 902 (33.2) | 585 (43.8) |
Cohabitation | ||||
Yes | 2490 (56.9) | 191 (59.3) | 1611 (59.3) | 688 (51.5) |
No | 1887 (43.1) | 131 (40.7) | 1107 (40.7) | 649 (48.5) |
Ethnicity | ||||
Denmark | 4101 (93.7) | 305 (94.7) | 2533 (93.2) | 1263 (94.5) |
Western | 106 (2.4) | < 5 | 70 (2.6) | < 35 |
Non-western | 170 (3.9) | < 15 | 115 (4.2) | < 45 |
Comorbidity | ||||
Diabetes mellitus | 735 (16.8) | 128 (39.8) | 324 (11.9) | 283 (21.2) |
Chronic Kidney disease | 183 (4.2) | 22 (6.8) | 82 (3.0) | 79 (5.9) |
Socioeconomic position | ||||
< 100,000 DKK | 432 (9.9) | 37 (11.5) | 257 (9.5) | 138 (10.3) |
100,000 – 299,999 | 3497 (79.9) | 261 (81.1) | 2134 (78.5) | 1102 (82.4) |
≥ 300,000 | 448 (10.2) | 24 (7.5) | 327 (12.0) | 97 (7.3) |
LLTb before or during index hospitalization | ||||
Statins | 1338 (30.6) | 233 (72.4) | 608 (22.4) | 497 (37.2) |
Ezetimibe | 21 (0.5) | < 5 | 16 (0.6) | < 5 |
Other non-statins | 13 (0.3) | < 5 | 6 (1.9) | < 10 |
Combinational treatment | 15 (0.3) | < 10 | 6 (1.9) | < 5 |
No treatment | 2990 (68.3) | 79 (24.5) | 2082 (76.6) | 829 (62.0) |
LLT intensityb before or during index hospitalization | ||||
No LLT | 2990 (68.3) | 79 (24.5) | 2082 (76.6) | 829 (62.0) |
Moderate LLTc | 1262 (28.8) | 220 (68.3) | 579 (21.3) | 463 (34.6) |
Intensive LLTd | 125 (2.9) | 23 (7.1) | 57 (2.1) | 45 (3.4) |
Lipid measurements before index hospitalizatione, N (%), mean ± SD | ||||
LDL-C | 2967 (67.8) 2.96 ± 1.12 | 272 (84.5) 1.86 ± 0.68 | 1733 (63.8) 3.22 ± 1.04 | 962 (72.0) 2.80 ± 1.14 |
HDL-C | 2968 (67.8) 1.33 ± 0.43 | 272 (84.5) 1.32 ± 0.48 | 1734 (63.8) 1.31 ± 0.39 | 962 (72.0) 1.37 ± 0.47 |
Total cholesterol | 2995 (68.4) 5.07 ± 1.28 | 272 (84.5) 3.97 ± 0.91 | 1750 (64.4) 5.33 ± 1.20 | 973 (72.8) 4.92 ± 1.31 |
Triglycerides | 2968 (67.8) 1.80 ± 1.23 | 272 (84.5) 1.84 ± 1.43 | 1734 (63.8) 1.86 ± 1.28 | 962 (72.0) 1.69 ± 1.07 |