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Table 2 HR and adjusted confounding factors of included studies

From: The predictive value of lymphocyte-to-monocyte ratio in the prognosis of acute coronary syndrome patients: a systematic review and meta-analysis

Study (year)

Outcomes

HR(95%CI)

Adjusted confounding factors

Gijsberts CM (2016) [18]

Long-term mortality

1.35 (1.14–1.59)

Leukocyte characteristics (lymphocyte cell size coefficient of variation, monocyte count)

Kiris T (2017) [21]

30-day mortality

36-month mortality

8.093 (1.006–65.074)

2.374 (1.160–4.857)

Age, gender, history of stroke/TIA, history of DM, multivessel disease, Killip, albumin, LVEF, hemoglobin, RDW, MPV, serum creatinine, total bilirubin, β-blocker usage, ACEI/ARB usage

Fan Z (2018) [22]

Long-term MACE

2.128 (1.458–3.105)

NLR, hs-CRP, brain natriuretic peptide

Cheng H (2019) [23]

In-hospital MACE

Long-term MACE

2.891 (1.265–8.354)

1.793 (1.169–2.515)

Age, male, body mass index, hypertension, DM, dyslipidemia, history of coronary artery disease, history of myocardial infarction, smoking index, Leukocyte, NLR, hs-CRP, gensini score

Cai M (2019) [24]

Long-term MACE

1.74 (1.12–2.70)

Age, sex, Killip, DM, hypertension, hyperlipidemia, PCI, β-blocker usage, ACEI/ARB usage, glucose, white blood cell, hemoglobin, ln CK-peak, MPV, RDW, LVEF, location of myocardial infarction

  1. Abbreviations: ACEI angiotensin-converting enzyme inhibitors, ARB angiotensin receptor blockers, CI confidence interval, DM diabetes mellitus, HR hazard ratio, hs-CRP high-sensitivity C reactive protein, LVEF left ventricular ejection fraction, MPV mean platelet volume, NLR neutrophil-to-lymphocyte ratio, PCI percutaneous coronary intervention, RDW red cell distribution width, TIA transient ischemic attack