Table 1 Characteristics of study cohort (n = 3002) at baseline according to JNC7 and the 2017 ACC/AHA guidelines for definition of hypertension, Tehran Lipid and Glucose Study (1999–2014)
|  | According to JNC7 | According to the 2017 ACC/AHA | Total population N = 3002 | ||||
|---|---|---|---|---|---|---|---|
Hypertensive n = 1301 | Normotensive n = 1701 | P-value | Hypertensive n = 2060 | Normotensive n = 942 | P-value | ||
Mean (SD) | Mean (SD) | Mean (SD) | |||||
Sex | |||||||
Male | 531 (40.8) | 891 (52.4) | < 0.001 | 897 (43.5) | 525 (55.7) | < 0.001 | 1422 (47.4) |
Female | 770 (59.2) | 810 (47.6) | 1163 (56.5) | 417 (44.3) | 1580 (52.6) | ||
Age (year) | 61.4(7.6) | 58.8(7.2) | < 0.001 | 60.5 (7.5) | 58.9 (7.4) | < 0.001 | 60.0(7.5) |
TC (mmol/L) | 6.07 (1.28) | 5.77 (1.18) | < 0.001 | 6.00 (1.25) | 5.68 (1.17) | < 0.001 | 5.90 (1.23) |
SBP (mmHg) | 149.9(19.7) | 119.1(11.4) | < 0.001 | 141.3 (20.0) | 113.04 (9.5) | < 0.001 | 132.4(21.8) |
DBP (mmHg) | 88.8(11.5) | 75.2(7.9) | < 0.001 | 86.01 (10.40) | 70.46 (6.17) | < 0.001 | 81.1(11.7) |
BMI (kg/m2) | 28.8(4.5) | 26.9(4.2) | < 0.001 | 28.4 (4.4) | 26.2 (4.2) | < 0.001 | 27.7(4.5) |
| Â | N (%) | Â | N (%) | Â | N (%) | ||
Smoking status | |||||||
Current | 103(7.9) | 293(17.2) | < 0.001 | 187 (9.1) | 209 (22.3) | < 0.001 | 396(13.1) |
Never | 1033(79.4) | 1211(71.1) | 1620 (78.8) | 624 (66.5) | 2244(74.7) | ||
Past | 162(12.4) | 192(11.2) | 248 (12.1) | 106 (11.3) | 354(11.7) | ||
Diabetes | |||||||
Yes | 386(29.6) | 294(17.2) | < 0.001 | 539 (27.0) | 141 (15.5) | < 0.001 | 680(22.6) |
No | 872(67.0) | 1353(79.5) | 1456 (73.0) | 769 (84.5) | 2225(74.1) | ||
Antihypertensive medication use | |||||||
yes | 498 (38.3) | 0 | Â | 498 (24.2) | 0 | Â | 498(16.6) |