Correlation of resting heart rate with anthropometric factors and serum biomarkers in a population-based study: Fasa PERSIAN cohort study

Table 2 Results of SCAD linear regression to modeling resting heart rate in Fasa PERSIAN (Prospective Epidemiological Research Study in IrAN) cohort

Variable	Model 1^a				Variable	Model 2^b
Variable	β	Standard β	SE	p- Value	Variable	β	Standard β	SE	p- Value
Sex (male is ref)	4.88	0.21	0.33	<0.001	Sex (male is ref)	4.62	0.22	0.211	<0.001
SBP	0.08	0.13	.006	<0.001	SBP	0.11	0.19	0.006	0.032
HDL.C	0.06	0.10	0.026	0.137	Beta1.blockers	−2.35	−0.07	0.021	0.006
WBC	0.34	0.17	.32	.288	Age	−0.05	− 0.05	− 0.03	0.012
GLUC	0.04	0.11	0.004	<0.001	BMI	0.08	0.04	0.07	0.003
Beta1.blockers	1.12	−0.06	0.002	<0.001	Opium	−1.89	−0.04	0.28	<0.001
TG	0.01	0.06	0.001	<0.001	Levothyroxine	−1.41	−0.02	0.42	<0.001
SGPT	0.006	0.009	0.007	0.39	Alpha. blockers	5.2	0.02	1.27	<0.001
DBP	0.171	0.193	0.009	.009	TCA	2.13	0.02	1.02	<0.001
Age	−.018	−.016	.011	.111	Metformin	1.20	0.02	0.13	0.001
SGOT	−.027	− 024	.12	.028	WC	0.39	0.003	0.043	0.008
BUN	−0.21	−0.08	.027	<0.001	SSRI	−1.00	− 0.01	− 0.91	<0.001
WC	0.12	0.05f	0.008	<0.001	WHR	2.29	0.01	0.031	<0.001
Opium	−1.69	−0.13	0.004	<0.001	Antihistamine	1.55	0.01	0.178	0.003
TCA	1.94	0.02	1.12	<0.001	Beta2.agonist	2.2	0.01	0.98	.002
Alpha. blockers	4.87	0.02	1.32	<0.001	Diuretics	0.64	0.01	0.24	0.001
HGB	0.09	0.01	0.02	<0.001
Levothyroxine	−0.93	−0.81	− 0.71	0.471
Metformin	−11.78	−10.36	−3.41	0.291
SSRI	−1.15	−0.01	−.98	0.003
Diuretics	0.87	0.005	0.73	0.004
LDL	−0.01	−0.003	−0.02	0.006
Beta2.agonist	0.88	0.002	0.56	0.042
Antihistamine	1.46	3.11	0.74	0.639
ABSI	−28.04	−0.001	−19.1	0.132

DBP Diastolic blood pressure, SBP Systolic blood pressure, BMI Body mass index, ABSI A body shape index, WHR Waist to hip ratio, WBC White blood cell, RBC Red blood cell, HGB Hemoglobin, HCT Hematocrit, MCV Mean cell volume, MCH Mean corpuscular hemoglobin, MCHC Mean corpuscular hemoglobin concentration, PLT Platelet, BUN Blood urea Nitrogen, Cr Creatinine, TG Triglyceride, SGOT Serum glutamic oxaloacetic transaminase, SGPT Serum glutamic pyruvic transaminase, ALP Alkaline phosphatase, HDL High-density lipoprotein, LDL Low-density lipoprotein, GGT Gamma glutamine transferase
^a Model 1, HR considered as dependent variable, and all of the other 41 factors (aforementioned in Table 1 and drugs) were considered as independent variables. The proposed model represents 25 variables as effective factors on resting heart rate
^b Only comprised age, sex, BMI, waist circumference, WHR, SBP, and drugs because the excluded variables show a bidirectional confounding relationship with RHR

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