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Table 5 COX proportional hazard model for the MACE of the study cohort

From: Comparison of the prognosis for different onset stage of cardiogenic shock secondary to ST-segment elevation myocardial infarction

 

Univariate

Multivariate

HR

95% CI

p-value

HR

95% CI

p-value

Age

1.028

1.016–1.040

< 0.001

1.017

1.005–1.031

0.005

Male sex

1.413

1.010–1.882

0.043

–

–

–

Hypertension

1.009

0.760–1.340

0.95

–

–

–

Diabetes

1.23

0.912–1.660

0.175

–

–

–

Smoking

0.812

0.617–1.068

0.136

–

–

–

Prior Stroke

1.863

1.338–2.594

< 0.001

1.639

1.146–2.344

0.007

Hyperlipdemia

0.909

0.545–1.514

0.713

–

–

–

Known kidney dysfunction

0.827

0.589–1.162

0.274

–

–

–

Prior MI

1.549

0.763–3.145

0.226

–

–

–

Pre-procedural SBP

0.996

0.990–1.002

0.213

–

–

–

Pre-procedural HR

1.005

0.997–1.013

0.192

–

–

–

LVEF, per % increased

0.962

0.940–0.984

0.001

0.978

0.954–0.997

0.044

TG, per mmol/L increased

0.892

0.770–1.032

0.124

–

–

–

TCh, per mmol/L increased

0.927

0.807–1.065

0.285

–

–

–

LDL-C, per mmol/L increased

0.989

0.933–1.048

0.700

–

–

–

HDL-C, per mmol/L increased

0.827

0.556–1.230

0.348

–

–

–

Multivessel lesions

1.444

1.091–1.911

0.01

1.462

1.098–1.947

0.009

Time of symptom-wire, per hour increased

1.003

0.994–1.013

0.477

–

–

–

IABP utility

1.108

0.665–1.847

0.693

–

–

–

Shock index (per 0.1 increased)

1.051

1.003–1.102

0.038

–

–

–

Anterior MI

0.739

0.562–0.972

0.031

–

–

–

Onset stage of CS

 Non- CS (reference)

1

–

–

1

–

–

 CS on admission

2.252

1.345–3.770

0.002

1.948

1.164–3.261

0.011

 developed CS

1.069

0.711–1.608

0.748

1.082

0.691–1.691

0.73

Killips Classification

 Killips = 1(reference)

1

–

–

–

–

–

 Killips = 2

1.34

0.933–1.925

0.113

–

–

–

 Killips = 3

1.864

0.914–3.801

0.087

–

–

–

 Killips = 4

2.389

1.423–4.013

0.001

–

–

–

post-PCI TIMI flow of IRA

 3 (reference)

1

–

–

1

–

–

 2

2.528

0.938–6.812

0.067

2.604

0.634–10.078

0.181

 1

3.38

0.837–13.643

0.087

3.108

1.130–8.026

0.02

  1. MACE Major adverse cardiac events, CS Cardiogenic shock, SBP Stytolic blood pressure, HR Heart rate, bpm beats per minute, LVEF Left ventricular ejection fraction, TG Triglyceride, LDL-C Low density lipoprotein cholesterol, HDL-C High density lipoprotein cholesterol, TC Total cholesterol, IABP Intra-aortic balloon pump, MI Myocardial infarction, TIMI Thrombolysis in myocardial infarction, IRA Infarct-related artery, PCI Percutaneous coronary intervention