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Table 1 Baseline characteristics according to neprilysin levels

From: Serum neprilysin levels are associated with myocardial stunning after ST-elevation myocardial infarction

 

Overall (n = 68)

Neprilysin level ≤ 125 pg/mL (n = 38)

Neprilysin level 126–450 pg/mL (n = 15)

Neprilysin level > 450 pg/mL (n = 15)

Overall p.value

Highest-level vs. lower groups p.value

Age, years

58.5 ± 12.8

59.8 ± 11.7

54.8 ± 9.8

60.5 ± 16.8

0.37

0.58

Gender, male

56 (82.4%)

31 (81.6%)

13 (86.7%)

12 (80.0%)

0.88

1

Hypertension

25 (36.8%)

11 (28.9%)

6 (40.0%)

8 (53.3%)

0.25

0.23

Diabetes mellitus

13 (19.1%)

7 (18.4%)

3 (20.0%)

3 (20.0%)

0.99

1

Hypercholesterolemia

33 (48.5%)

19 (50.0%)

6 (40.0%)

8 (53.3%)

0.74

0.90

Current smoking

43 (63.2%)

26 (86.4%)

8 (53.3%)

9 (60.0%)

0.57

1

Body Mass Index, kg/m2

26.1 [24.0, 29.4]

26.0 [23.6, 29.3]

28.5 [26.3, 29.3]

25.8 [23.4, 30.0]

0.45

0.75

Heart rate, bpm

77 ± 17

75 ± 15

80 ± 19

78 ± 20

0.62

0.77

Systolic BP, mmHg

142 ± 25

145 ± 28

134 ± 22

145 ± 22

0.39

0.65

Diastolic BP, mmHg

85 ± 19

87 ± 16

78 ± 21

86 ± 22

0.26

0.83

Anterior STEMI

27 (39.7%)

15 (39.5%)

6 (40.0%)

6 (40.0%)

1

1

Symptoms to balloon, hours

4.7 [3.1, 8.7]

4.5 [3.2, 6.0]

3.7 [2.7, 8.6]

6.8 [3.9, 10.8]

0.36

0.18

Thrombolysis

2 (2.9%)

1 (2.6%)

0

1 (6.7%)

0.69

0.40

GFR, mL/min/1.73m2

93 ± 17

91 ± 16

96 ± 19

93 ± 16

0.65

0.88

  1. BP blood pressure, GFR glomerular filtration rate, STEMI ST-elevation myocardial infarction