Skip to main content

Table 1 Baseline characteristics according to neprilysin levels

From: Serum neprilysin levels are associated with myocardial stunning after ST-elevation myocardial infarction

  Overall (n = 68) Neprilysin level ≤ 125 pg/mL (n = 38) Neprilysin level 126–450 pg/mL (n = 15) Neprilysin level > 450 pg/mL (n = 15) Overall p.value Highest-level vs. lower groups p.value
Age, years 58.5 ± 12.8 59.8 ± 11.7 54.8 ± 9.8 60.5 ± 16.8 0.37 0.58
Gender, male 56 (82.4%) 31 (81.6%) 13 (86.7%) 12 (80.0%) 0.88 1
Hypertension 25 (36.8%) 11 (28.9%) 6 (40.0%) 8 (53.3%) 0.25 0.23
Diabetes mellitus 13 (19.1%) 7 (18.4%) 3 (20.0%) 3 (20.0%) 0.99 1
Hypercholesterolemia 33 (48.5%) 19 (50.0%) 6 (40.0%) 8 (53.3%) 0.74 0.90
Current smoking 43 (63.2%) 26 (86.4%) 8 (53.3%) 9 (60.0%) 0.57 1
Body Mass Index, kg/m2 26.1 [24.0, 29.4] 26.0 [23.6, 29.3] 28.5 [26.3, 29.3] 25.8 [23.4, 30.0] 0.45 0.75
Heart rate, bpm 77 ± 17 75 ± 15 80 ± 19 78 ± 20 0.62 0.77
Systolic BP, mmHg 142 ± 25 145 ± 28 134 ± 22 145 ± 22 0.39 0.65
Diastolic BP, mmHg 85 ± 19 87 ± 16 78 ± 21 86 ± 22 0.26 0.83
Anterior STEMI 27 (39.7%) 15 (39.5%) 6 (40.0%) 6 (40.0%) 1 1
Symptoms to balloon, hours 4.7 [3.1, 8.7] 4.5 [3.2, 6.0] 3.7 [2.7, 8.6] 6.8 [3.9, 10.8] 0.36 0.18
Thrombolysis 2 (2.9%) 1 (2.6%) 0 1 (6.7%) 0.69 0.40
GFR, mL/min/1.73m2 93 ± 17 91 ± 16 96 ± 19 93 ± 16 0.65 0.88
  1. BP blood pressure, GFR glomerular filtration rate, STEMI ST-elevation myocardial infarction