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Table 1 Clinical Characteristics

From: Restricted mean survival time of older adults with severe aortic stenosis referred for transcatheter aortic valve replacement

 

Total (N = 373)

TAVR (n = 233)

No TAVR (n = 140)

P-value

DEMOGRAPHICS

 Age, years

82.4 ± 6.6

81.4 ± 6.3

84 ± 6.6

< 0.001

 Female sex

184 (49%)

108 (46%)

76 (54%)

0.14

 Body Mass Index, kg/m2

27.1 ± 6

27.4 ± 6.1

26.3 ± 5.7

0.12

COMORBIDITIES

 Diabetes mellitus

80 (21%)

66 (28%)

14 (10%)

< 0.001

 Coronary artery disease

196 (53%)

137 (59%)

59 (42%)

0.002

 Prior myocardial infarction

38 (10%)

26 (11%)

12 (9%)

0.42

 Prior stroke

19 (5%)

17 (7%)

2 (1%)

0.01

 Peripheral arterial disease

24 (6%)

19 (8%)

5 (4%)

0.08

 Chronic kidney disease

187 (50%)

104 (45%)

83 (59%)

0.006

 Dialysis-dependent

7 (2%)

5 (2%)

2 (2%)

0.85

 Cirrhosis

7 (2%)

5 (2%)

2 (1%)

0.62

 NYHA class

2.5 ± 0.6

2.4 ± 0.6

2.5 ± 0.7

0.15

ECHOCARDIOGRAM

 LVEF ≤35%

34 (9%)

15 (7%)

19 (14%)

0.02

 PASP ≥60 mmHg

50 (13%)

27 (12%)

23 (16%)

0.18

 Mean aortic gradient, mmHg

49.5 ± 18.3

52 ± 17.7

45.4 ± 18.6

< 0.001

  1. Abbreviations: LVEF left ventricular ejection fraction, NYHA New York Heart Association, PASP pulmonary artery systolic pressure, TAVR transcatheter aortic valve replacement