Effects of trimetazidine on ventricular remodeling in coronary artery disease patients with left ventricular hypertrophy: the rationale and design of a randomized controlled trial

Table 1 Study plan

Activity	Visit 0 screening	Visit 1	Visit 2
Activity	0 day	3 months ±7 day	12 months ±7 day
Inclusion/exclusion criteria	×
Informed consent	×
Randomization	×
Demography and medical history	×
Physical examination	×	×	×
12-lead ECG	×	×	×
Concomitant medication	×	×	×
CBC	×	×	×
Scr, BUN, UA	×	×	×
ALT, AST	×	×	×
TC, LDL-C, HDL-C, TG	×	×	×
NT-proBNP	×	×	×
cTnT/cTnI	×
Echocardiography	×	×	×
Symptoms of angina	×	×	×
6 min walk test	×	×	×
Exercise electrocardiography test	×	×	×
MACEs		×	×
Quality of life	×	×	×

ECG Electrocardiography, CBC complete blood count, Scr serum creatinine, BUN blood urea nitrogen, UA uric acid, ALT alanine aminotransferase, AST aspartate aminotransferase, TC total cholesterol, LDL-C low-density lipoprotein cholesterol, HDL-C how-density lipoprotein cholesterol, TG triglyceride, NT-proBNP N-terminal pro-B–type natriuretic peptide, cTnT/cTnI cardiac troponin-T/ cardiac troponin-I, MACEs major adverse cardiovascular events

ISSN: 1471-2261