Baseline | First week after TAVR | 3 months after TAVR | baseline vs. first week (Mean difference [95% CI], p value) | baseline vs. 3 months (Mean difference [95% CI], p value) | p value (ANOVA) | |
---|---|---|---|---|---|---|
LVEF [%] | 50.27 ± 11.13 | 52.90 ± 10.58 | 53.51 ± 8.8 | −2.62 [− 4,11; − 1.14], p < 0.01 | − 1.43 [− 3.04; 0.17], p < 0.05 | NS |
LVEDV [ml] | 106 ± 46 | 113 ± 53 | 98 ± 543 | −6.76 [− 16.30; − 1.41], p = NS | 2.42 [−8.24; 13.10], p = NS | NS |
LVESV [ml] | 59 ± 36 | 58 ± 38 | 51 ± 32 | 1.70 [− 3.49; 6.89], p = NS | 23.12 [− 18.01; 64.26], p = NS | NS |
LV mass Index [g/m2] | 152 ± 56 | 158 ± 58 | 133.42 ± 55.8 | −5.58 [− 16.78; 5.06], p = NS | −6.76 [− 16.30; − 1.41], p = NS | NS |
AVAc [cm2] | 0.6 ± 0.16 | 1.8 ± 0.8 | 1.52 ± 0.3 | − 1.36 [− 1.75; − 0.97], p < 0.001 | −1.19 [− 1.60; − 0.78], p < 0.001 | < 0.001 |
Mean PG [mmHg] | 42.4 ± 14.5 | 9.9 ± 4.7 | 9.33 ± 4.7 | 32.48 [29.99; 34.97], p < 0.001 | 32.03 [29.05;35.02], p < 0.001 | < 0.001 |
sPAP [mmHg] | 45.7 ± 16.7 | 47.6 ± 17.1 | 43.5 ± 12.5 | −1.89 [− 5.02; 1.23], p = NS | 2.06 [− 1.17; 5.30], p = NS | NS |
E’ lateral | 7.4 ± 2.2 | 7.5 ± 2.4 | 7.7 ± 2.7 | − 0.17 [− 0.74; 0.48], p = NS | − 0.53 [− 1.29; − 0.22], p = NS | NS |
E/E’ | 13.6 ± 5.6 | 14.6 ± 6.6 | 14.3 ± 7.8 | − 1.02 [− 2.59; 0.55], p = NS | − 1.06 [− 3.28; − 1.15], p = NS | NS |
TAPSE | 17.9 ± 5.2 | 18.4 ± 4.8 | 19.7 ± 5.4 | −0.5 [− 1.48; 0.39], p = NS | −0.53 [− 1.82; 0.76], p = NS | NS |
GLS [%] | − 15.9 ± 4.33 | − 16.84 ± 4.1 | −19.5 ± 3.5 | 0.93 [− 0.73; 2.60], p = NS | 3.84 [2.72; 4.96], p < 0.001 | < 0.001 |
GCS [%] | −28.03 ± 12 | −20.25 ± 10 | −30.06 ± 7.2 | 0.22 [− 4.23; 4.67], p = NS | 1.91 [− 2.17; 6.01], p = NS | NS |
GRS [%] | 66.3 ± 30.5 | 60.25 ± 18.2 | 64.2 ± 14.02 | 6.37 [−9.68; 22.43], p = NS | 2.2 [− 10.35; 14.75], p = NS | NS |