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Table 2 Cardiovascular outcomes of all patients

From: Incremental prognostic value of aortic stiffness in addition to myocardial ischemia by cardiac magnetic resonance imaging

 

Group 1

Lower PWV-Negative ischemia

Group 2

Lower PWV-Positive ischemia

Group 3

Higher PWV-Negative ischemia

Group 4

Higher PWV-Positive ischemia

Event Rate (%)

Event Rate (%)

Unadjusted HR,

p-value

Adjusted HR model 1,

p-value

Adjusted HR model 2,

p-value

Event Rate (%)

Unadjusted HR, p-value

Adjusted HR model 1,

p-value

Adjusted HR model 2,

p-value

Event Rate (%)

Unadjusted HR,

p-value

Adjusted HR model 1,

p-value

Adjusted HR model 2,

p-value

All-cause Mortality

6 (3.6)

10 (11.0)

3.17, 0.03

3.13, 0.03

3.54, 0.02

3 (2.0)

0.61, 0.49

0.59, 0.47

0.62, 0.51

9 (8.3)

2.77, 0.05

3.01, 0.04

2.85, 0.08

CV Mortality

1 (0.6)

5 (5.5)

9.52, 0.04

8.53, 0.05

5.05, 0.17

0

N/A

N/A

N/A

4 (3.7)

7.35, 0.07

7.93, 0.07

4.20, 0.25

ACS

3 (1.8)

8 (8.8)

5.18, 0.02

5.49, 0.01

4.80, 0.03

8 (5.3)

3.39, 0.07

3.19, 0.09

2.95, 0.12

22 (20.4)

15.14, <  0.001

15.41, <  0.001

12.09, <  0.001

Heart failure

5 (3.0)

12 (13.2)

4.78, 0.003

4.72, 0.004

3.60, 0.02

12 (7.9)

2.71, 0.06

2.47, 0.09

2.91, 0.06

25 (23.1)

10.03, <  0.001

11.18, <  0.001

8.06, <  0.001

Revascularization

0

6 (6.6)

N/A

N/A

N/A

3 (2.0)

N/A

N/A

N/A

20 (18.5)

N/A

N/A

N/A

Stroke

1 (0.6)

2 (2.2)

3.89, 0.30

3.55, 0.13

3.00, 0.38

5 (3.3)

6.42, 0.09

5.42, 0.13

6.09, 0.11

6 (5.6)

11.94, 0.02

10.31, 0.03

7.98, 0.07

Combined CV Outcomes

14 (8.3)

25 (27.5)

3.67, <  0.001

3.66, <  0.001

2.68, 0.005

24 (15.8)

2.19, 0.02

2.24, 0.02

2.29, 0.02

53 (49.1)

8.94, <  0.001

9.86, <  0.001

6.67, <  0.001

  1. Bold values are statistically significant
  2. The group 1 (lower PWV with negative ischemia) is the reference group
  3. Model 1 is adjusted for age, gender, and systolcic blood pressure
  4. Model 2 is adjusted for age, gender, systolic blood pressure, BMI, hypertension, diabetes mellitus, known CAD, current smoking, and LVEF
  5. ACS Acute coronary syndrome, BMI Body mass index, CAD Coronary artery disease, CV Cardiovascular, HR Hazard ratio, LVEF Left ventricular ejection fraction, N/A Not available, PWV Pulse wave velocity