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Table 1 Clinical characteristics of patients with AF on admission

From: BMI differences among in-hospital management and outcomes in patients with atrial fibrillation: findings from the Care for Cardiovascular Disease project in China

Variables

Total

N = 15,867

Underweight

BMI < 18.5

(n = 830)

Normal

18.5 ≤ BMI < 23

(n = 4965)

Overweight

23 ≤ BMI < 25

(n = 3716)

Obese, class I

25 ≤ BMI < 30

(n = 5263)

Obese, class II

BMI ≥ 30

(n = 1093)

p value

Age

68.09 ± 11.93

72.42 ± 12.69

69.46 ± 12.01

68.11 ± 11.65

66.62 ± 11.57

65.64 ± 11.90

< 0.001

Male

8860 (55.8)

352 (42.4)

2610 (52.6)

2158 (58.1)

3189 (60.6)

551 (50.4)

< 0.001

Current smoker

3421 (21.6)

147 (17.7)

990 (19.9)

764 (20.6)

1291 (24.5)

229 (21.0)

< 0.001

Current drinking

1808 (11.4)

60 (7.2)

476 (9.6)

412 (11.1)

722 (13.7)

138 (12.6)

< 0.001

Comorbidities

 Hypertension

8504 (53.6)

296 (35.7)

2306 (46.4)

1954 (52.6)

3205 (60.9)

743 (68.0)

< 0.001

 Diabetes mellitus

2712 (17.1)

68 (8.2)

641 (12.9)

666 (17.9)

1064 (20.2)

273 (25.0)

< 0.001

 CAD

3667 (23.1)

180 (21.7)

1073 (21.6)

909 (24.5)

1236 (23.5)

269 (24.6)

0.012

 CHF

2194 (13.8)

171 (20.6)

747 (15.0)

500 (13.5)

642 (12.2)

134 (12.3)

< 0.001

 Stroke

2024 (12.8)

113 (13.6)

628 (12.6)

489 (13.2)

658 (12.5)

136 (12.4)

0.820

 Renal failure

396 (2.4)

39 (4.7)

129 (2.6)

81 (2.2)

130 (2.5)

17 (1.6)

< 0.001

 Underwent dialysis

22 (5.5)

2 (5.1)

10 (7.8)

3 (3.7)

6 (4.6)

1 (5.9)

0.002

 Renal transplant

7 (1.8)

0 (0)

3 (2.3)

0 (0)

4 (3.1)

0 (0)

0.001

 Rheumatic heart disease

887 (5.6)

105 (12.7)

386 (7.8)

198 (5.3)

169 (3.2)

29 (2.7)

< 0.001

 COPD

613 (3.9)

57 (6.9)

202 (4.1)

132 (3.6)

179 (3.4)

43 (3.9)

< 0.001

 Cancer

260 (1.6)

27 (3.3)

105 (2.1)

61 (1.6)

55 (1.0)

12 (1.1)

< 0.001

 First diagnosis of AF

1609 (10.1)

84 (10.1)

482 (9.7)

403 (10.8)

545 (10.4)

95 (8.7)

< 0.001

 Non-valvular AF

13,792 (86.9)

610 (73.5)

4106 (82.7)

3265 (87.9)

4796 (91.1)

1015 (92.9)

< 0.001

On admission value

 HR at rest (bmp/min)

88.64 ± 27.68

93.45 ± 29.77

88.57 ± 27.90

88.05 ± 27.92

87.87 ± 26.85

91.03 ± 27.35

< 0.001

 SBP (mmHg)

130.57 ± 20.45

123.69 ± 21.04

128.50 ± 20.57

130.50 ± 20.47

132.64 ± 19.85

135.45 ± 19.81

< 0.001

 DBP (mmHg)

78.82 ± 13.33

74.11 ± 13.52

77.10 ± 13.12

78.69 ± 13.15

80.46 ± 13.21

82.74 ± 13.20

< 0.001

 QTc (ms)

419.22 ± 64.13

416.15 ± 60.39

418.82 ± 65.16

417.48 ± 61.78

419.31 ± 62.92

428.15 ± 59.31

0.003

 LVEDd (ms)

49.99 ± 8.18

48.26 ± 9.41

49.75 ± 8.71

49.82 ± 8.02

50.36 ± 7.74

51.00 ± 7.18

< 0.001

 LAAP (mm)

42.73 ± 9.11

43.42 ± 11.75

42.39 ± 9.46

42.11 ± 9.21

43.02 ± 8.33

44.28 ± 8.46

< 0.001

LVEF

      

< 0.001

  < 40%

1151 (7.3)

77 (9.3)

421 (8.5)

241 (6.5)

338 (6.4)

74 (6.8)

 40–49%

1463 (9.2)

95 (11.4)

468 (9.4)

354 (9.5)

450 (8.6)

96 (8.8)

  ≥ 50%

13,253 (83.5)

658 (79.3)

4076 (82.1)

3121 (84.0)

4475 (85.0)

923 (84.4)

CHADS2score

      

0.001

 0–1

9541 (60.1)

489 (58.9)

3058 (61.6)

2265 (61.0)

3126 (59.4)

603 (55.2)

 2

3519 (22.2)

196 (23.6)

1088 (21.9)

773 (20.8)

1179 (22.4)

283 (25.9)

 3–6

2782 (17.5)

141 (17.0)

809 (16.3)

670 (18.0)

955 (18.1)

207 (18.9)

CHA2DS2-VAS score

      

< 0.001

 0–1

4646 (29.3)

184 (22.2)

1396 (28.1)

1101 (29.6)

1674 (31.8)

291 (26.6)

 2–4

9082 (57.2)

519 (62.5)

2937 (59.2)

2107 (56.7)

2881 (54.7)

638 (58.4)

 5–9

2114 (13.3)

123 (14.8)

622 (12.5)

500 (13.5)

705 (13.4)

164 (15.0)

Medication history

 Beta-blocker

4485 (28.3)

190 (22.9)

1289 (26.0)

1002 (27.0)

1633 (31.0)

371 (33.9)

< 0.001

 CCB

2361 (14.9)

76 (9.2)

601 (12.1)

500 (13.5)

982 (18.7)

202 (18.5)

< 0.001

 Antiarrhythmic agents

1404 (8.8)

35 (4.2)

378 (7.6)

329 (8.9)

540 (10.3)

122 (11.2)

< 0.001

 Antiplatelet agents

1137 (7.2)

48 (5.8)

351 (7.1)

286 (7.7)

359 (6.8)

93 (8.5)

0.094

 Warfarin

2097 (13.2)

118 (14.2)

653 (13.2)

509 (13.7)

668 (12.7)

149 (13.6)

0.127

 Aspirin

3302 (20.8)

114 (13.7)

952 (19.2)

786 (21.2)

1185 (22.5)

265 (24.2)

< 0.001

  1. Data are mean ± SD for normally distributed data and median and interquartile range for non-normally distributed data, or n (%)
  2. AF indicates atrial fibrillation; BMI Body mass index; CAD Coronary artery disease; CCB Calcium channel blocker; CHF Chronic heart failure; COPD Chronic obstructive pulmonary disease; DBP Diastolic blood pressure; HR Heart rate; LAAP Left atrium diameter; LVEDd Left ventricular end-diastolic dimension; SBP systolic blood pressure; LVEF Left ventricular ejection fraction; QTc Corrected QT interval; CHADS2 score, congestive heart failure, hypertension, age 75 years of older, diabetes mellitus, prior stroke and TIA; CHA2DS2-VAS score, congestive heart failure, hypertension, age 75 years of older, diabetes mellitus, previous stroke/transient ischemic attack, vascular disease, age 65–74 years, female