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Table 5 Combined effect on serum uric acid and urinary sodium excretion on the risk of prehypertension from normotension

From: The effect of uric acid and urinary sodium excretion on prehypertension: a nationwide population-based study

 

Urinary sodium excretion

  

Tertile 1

Tertile 2

Tertile 3

ORs (95% CI) for T2 of urinary sodium excretion within strata of serum uric acid tertiles

ORs (95% CI) for T3 of urinary sodium excretion within strata of serum uric acid tertiles

OR

95% CI

OR

95% CI

OR

95% CI

Serum uric acid

Tertile 1

Reference

 

1.520

1.053–2.195

2.015

1.427–2.844

1.520

1.053–2.195

2.015

1.427–2.844

Tertile 2

1.155

0.805–1.657

1.654

1.157–2.364

2.771

1.931–3.976

1.432

0.989–2.074

2.400

1.672–3.443

Tertile 3

2.582

1.805–3.693

3.580

2.570–4.988

3.679

2.608–5.191

1.386

1.016–1.892

1.425

1.031–1.970

ORs (95% CI) for T2 of uric acid within strata of Urinary sodium excretion tertiels

1.155

0.805–1.657

1.088

0.782–1.513

1.375

0.978–1.934

    

ORs (95% CI) for T3 of uric acid within strata of Urinary sodium excretion tertiels

2.582

1.805–3.693

2.355

1.764–3.144

1.826

1.357–2.459

    

Measure of interaction on additive scale: RERI (95% CI)

    

0.293a

0.036–0.549

    
  

0.810b

−0.450 - 2.06

1.856c

−1.078 - 4.790

    

Measure of interaction on multiplicative scale: Ratio of ORs (95% CI)

    

1.191d

0.740–1.918

    
  

0.912e

0.571–1.458

0.841f

0.662–1.069

    
  1. a,cMeasure of interaction for tertile 3 urinary sodium excretion and tertile 2 serum uric acid; b,eMeasure of interaction for tertile 2 urinary sodium excretion and tertile 3 serum uric acid; c,fMeasure of interaction for tertile 3 urinary sodium excretion and tertile 3 serum uric acid
  2. OR odds ratio, CI confidence interval, RERI relative excess risk due to interaction