Fig. 1
IR induced myocardial injury in rats. a The levels of LVEF, LVEDV, LVESV, LVSP, LVEDP, +dP/dtmax and -dP/dtmax (N = 25 each group). b Infarct size (N = 10 each group). c HE staining of myocardial tissues (× 400, N = 5 each group, representative images were shown). d The levels of IL-1β, IL-6 and TNF-α were detected by ELISA (N = 10 each group). e The apoptotic cells (%) were measured by TUNEL staining (N = 5 each group, representative images were shown). f The expression of Bax, Bcl-2 and caspase-3 was detected by Western blot (N = 5 each group, representative images were shown). g The expression of rno-miR-30c-5p was detected by qRT-PCR (N = 5 each group). h The expression of p-IκBα, IκBα, p-NF-κB p65 and NF-κB p65 was detected by Western blot (N = 5 each group, representative images were shown). Data were presented as mean ± SD (three independent repetitions for each sample). *P < 0.05, vs. Sham group