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Table 3 Differences in use of lipid-lowering medication and meeting treatment targets for lipids by study

From: Pharmacological management of modifiable cardiovascular risk factors (blood pressure and lipids) following diagnosis of myocardial infarction, stroke and diabetes: comparison between population-based studies in Russia and Norway

 

KYH

Tromsø 7

ORc (Tromsø 7/KYH) adjusted for age and sex (95% CI)

ORc (Tromsø 7/KYH) adjusted for age, sex and education (95% CI)

ORc (Tromsø 7/KYH) adjusted for age, sex, education and visiting a doctor in the past 12 months (95% CI)

n/total N

Age and sex standardised %a

n/total N

Age and sex standardised %a

MI

Use of lipid-lowering medication

91/236

30.2

270/373

78.5

4.23 (2.94, 6.08)

4.34 (2.97, 6.36)

3.94 (2.67, 5.81)

Meets treatment target for lipid levelsb

36/236

5.1

41/332

10.1

1.52 (0.80,2.88)

1.33 (0.68, 2.58)

1.29 (0.65, 2.53)

Meets treatment target for lipid levelsb

and on medication

27/91

10.9

32/270

10.9

0.87 (0.41, 1.84)

0.77 (0.35, 1.67)

0.75 (0.34, 1.64)

LDL-C ≥ 4 mmol/L

48/236

24.2

43/373

10.0

0.44 (0.27, 0.69)

0.44 (0.27, 0.72)

0.47 (0.29, 0.77)

Stroke

Use of lipid-lowering medication

43/143

22.3

144/307

38.9

2.31 (1.49, 3.58)

2.20 (1.40, 3.47)

2.08 (1.31, 3.28)

Meets treatment target for lipid levelsb

25/143

11.6

21/307

5.8

0.61 (0.30, 1.28)

0.62 (0.29, 1.33)

0.60 (0.28, 1.28)

Meets treatment target for lipid levelsband on medication

21/43

41.9

17/144

9.2

0.25 (0.10, 0.59)

0.25 (0.10, 0.65)

0.25 (0.10, 0.65)

LDL-C ≥ 4 mmol/L

29/143

29.7

48/307

19.9

0.24 (0.15, 0.39)

0.20 (0.12, 0.34)

0.20 (0.12, 0.34)

Diabetes

Use of lipid-lowering medication

88/336

22.6

272/786

30.7

1.78 (1.32, 2.40)

1.71 (1.25, 2.34)

1.66 (1.21, 2.28)

Meets treatment target for lipid levelsb

118/336

24.9

191/786

23.3

1.01 (0.74, 1.39)

1.01 (0.73, 1.40)

1.00 (0.72, 1.40)

Meets treatment target for lipid levelsb and on medication

56/88

33.3

112/272

42.7

0.83 (0.50, 1.37)

0.85 (0.50, 1.44)

0.86 (0.51, 1.45)

LDL-C ≥ 4 mmol/L

64/336

21.5

182/786

23.7

0.46 (0.28, 0.75)

0.40 (0.23, 0.68)

0.40 (0.23, 0.68)

  1. a Denominator is participants with included data on LDL-C (LDL-C missing for 9 participants in Know Your Heart; 10 participants Tromsø 7)
  2. bTreatment targets LDL-C < 1. 8 mmol/L for MI/stroke and diabetes with co-morbid stroke/ MI and < 2.6 mmol/L for diabetes with no co-morbid stroke/MI
  3. cExcluding those with missing data on education or visiting a doctor in the past 12 months