Association of methylenetetrahydrofolate reductase (MTHFR) variant C677T and risk of carotid atherosclerosis: a cross-sectional analysis of 730 Chinese Han adults in Chongqing

Table 2 Risk factors of hyperhomocysteinemia by Binary logistic analysis

	B-value	SE	Wald	P-value	OR	95%CI
Age	1.196	0.304	15.52	< 0.001^*	3.31	1.82 ~ 6.00
Gender	1.445	0.434	11.059	0.001^*	4.24	1.81 ~ 9.94
Smoking	0.320	0.273	1.371	0.242	1.38	0.81 ~ 2.35
Drinking	0.089	0.287	0.097	0.755	1.09	0.62 ~ 1.92
Dietary habit	−0.078	0.264	0.086	0.769	0.93	0.55 ~ 1.55
Hypertension	0.461	0.269	2.938	0.087	1.59	0.94 ~ 2.69
FBG
< 5.5 mmol/L			2.811	0.245
5.5–7 mmol/L	−0.002	0.284	0.000	0.995	1.00	0.57 ~ 1.74
≧7 mmol/L	−0.684	0.426	2.573	0.109	0.51	0.22 ~ 1.16
MTHFR C677T
CC			68.307	< 0.001^*
CT	0.189	0.321	0.348	0.555	1.21	0.65 ~ 2.27
TT	2.456	0.343	51.366	< 0.001^*	11.66	5.96 ~ 22.83

Age(y): <60 = 0,≥60 = 1; Gender: Female = 0,Male = 1; Dietary habit: low-salt and/or low-fat =0, high-salt and/or high-fat = 1; Smoking:
No =0, yes = 1.Drinking: No = 0, Yes = 1. Hypertension: normal = 0, Hypertension = 1. ^*P<0.05 was considered to be statistically significant

ISSN: 1471-2261