Fig. 2

Receiver operating characteristic analysis to compare the diagnostic performance of Framingham risk score, age, male gender, HDL-C, and total cholesterol for prediction of CAC progression. Among these parameters, Framingham risk score with the cut-off ≥11.1 had the better discriminative ability to predict CAC progression compared to the other parameters with a sensitivity of 75.24% and specificity of 53.95% (AUC =0.660, PPV = 32.60%; NPV = 88.00%)